Mitochondrial Fission and Fusion in Tumor Progression to Metastasis

Mitochondria are highly dynamic organelles which can change their shape, via processes termed fission and fusion, in order to adapt to different environmental and developmental contexts. Due to the importance of these processes in maintaining a physiologically healthy pool of mitochondria, aberrant...

Full description

Bibliographic Details
Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Dillon P. Boulton, M. Cecilia Caino
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-03-01
Subjects:	mitochondria cancer metastasis mitochondrial dynamics fission fusion
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.849962/full

Similar Items

Mitochondrial Dynamics: Fission and Fusion in Fate Determination of Mesenchymal Stem Cells
by: Lin Ren, et al.
Published: (2020-10-01)

Mitochondrial fusion–fission dynamics and its involvement in colorectal cancer
by: Zihong Wu, et al.
Published: (2024-05-01)

Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders
by: Mode Al Ojaimi, et al.
Published: (2022-09-01)

Recent Advances in Mitochondrial Fission/Fusion-Targeted Therapy in Doxorubicin-Induced Cardiotoxicity
by: Chayodom Maneechote, et al.
Published: (2023-04-01)

Abnormal expression of fission and fusion genes and the morphology of mitochondria in eutopic and ectopic endometrium
by: Chaoshuang Ye, et al.
Published: (2023-07-01)

Redox Modifications of Proteins of the Mitochondrial Fusion and Fission Machinery
by: Christina Wolf, et al.
Published: (2020-03-01)

The Imbalance of Mitochondrial Fusion/Fission Drives High-Glucose-Induced Vascular Injury
by: Yunsi Zheng, et al.
Published: (2021-11-01)

Mitochondrial fission and fusion in astrocytes: a new pathway towards senescence
by: Sonia Luz Albarracin
Published: (2015-02-01)

Genetic Neuropathy Due to Impairments in Mitochondrial Dynamics
by: Govinda Sharma, et al.
Published: (2021-03-01)

Morphological Pathways of Mitochondrial Division
by: Bernard Tandler, et al.
Published: (2018-02-01)

Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice
by: Liu Xie, et al.
Published: (2025-05-01)

A platinum(IV)–artesunate complex triggers ferroptosis by boosting cytoplasmic and mitochondrial lipid peroxidation to enhance tumor immunotherapy
by: Renming Fan, et al.
Published: (2024-06-01)

The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial Membranes
by: James Chapman, et al.
Published: (2020-08-01)

An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
by: Tricia T Nguyen, et al.
Published: (2022-11-01)

Integrating multiple aspects of mitochondrial dynamics in neurons: Age-related differences and dynamic changes in a chronic rotenone model
by: Beth Arnold, et al.
Published: (2011-01-01)

Clinical and Biochemical Features in a Patient With Mitochondrial Fission Factor Gene Alteration
by: Alessia Nasca, et al.
Published: (2018-12-01)

MTFR2-dependent mitochondrial fission promotes HCC progression
by: La Zhang, et al.
Published: (2024-01-01)

Mitochondrial Dynamics in Mitochondrial Diseases
by: Juan M. Suárez-Rivero, et al.
Published: (2016-12-01)

Modulation of Mitochondrial Dynamics in Primary Hippocampal Cultures of 5xFAD Mice by Mdivi-1, MFP, and Exogenous Zinc
by: Alina Chaplygina, et al.
Published: (2025-09-01)

Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics
by: Alvaro M. Gonzalez-Ibanez, et al.
Published: (2020-11-01)

Mitochondrial dynamics at the intersection of macrophage polarization and metabolism
by: Pan Li, et al.
Published: (2025-03-01)

Modulation of mitochondrial dynamics in skeletal muscle during endurance training: early activation of fission and late induction of fusion protein expression
by: Hisashi Takakura, et al.
Published: (2025-01-01)

Attenuation of PM2.5-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion
by: Qi Liu, et al.
Published: (2023-07-01)

All-Trans Retinoic Acid Increases DRP1 Levels and Promotes Mitochondrial Fission
by: Bojjibabu Chidipi, et al.
Published: (2021-05-01)

Mitochondrial dynamics and colorectal cancer biology: mechanisms and potential targets
by: Zihong Wu, et al.
Published: (2024-02-01)

Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction
by: Jia Guo, et al.
Published: (2022-10-01)

Mitochondrial Dynamics in Ovarian Cancer: Pathophysiology and Therapeutic Implications
by: Hiroshi Kobayashi, et al.
Published: (2023-11-01)

Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting
by: Jean-Philippe Leduc-Gaudet, et al.
Published: (2020-06-01)

Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology
by: Jin Yu, et al.
Published: (2016-11-01)

Aberrant Mitochondrial Fission Is Maladaptive in Desmin Mutation–Induced Cardiac Proteotoxicity
by: Shafiul Alam, et al.
Published: (2018-07-01)

Mechanical force induces mitochondrial fission
by: Sebastian Carsten Johannes Helle, et al.
Published: (2017-11-01)

VPS13D affects epileptic seizures by regulating mitochondrial fission and autophagy in epileptic rats
by: Jian Wang, et al.
Published: (2024-11-01)

Alternative splicing of Mff regulates AMPK-mediated phosphorylation, mitochondrial fission and antiviral response
by: Yuki Hanada, et al.
Published: (2024-11-01)

Mitochondrial Dynamics: A Key Role in Neurodegeneration and a Potential Target for Neurodegenerative Disease
by: Danying Yang, et al.
Published: (2021-04-01)

The Alterations in Mitochondrial Dynamics Following Cerebral Ischemia/Reperfusion Injury
by: Jirapong Vongsfak, et al.
Published: (2021-08-01)

Bezafibrate Improves Mitochondrial Fission and Function in DNM1L-Deficient Patient Cells
by: Liza Douiev, et al.
Published: (2020-01-01)

Mitochondrial Quality Control in the Heart: The Balance between Physiological and Pathological Stress
by: Giovanni Fajardo, et al.
Published: (2022-06-01)

Photobiomodulation provides neuroprotection through regulating mitochondrial fission imbalance in the subacute phase of spinal cord injury
by: Xin Li, et al.
Published: (2023-01-01)

Comparative Untargeted Metabolomic Profiling of Induced Mitochondrial Fusion in Pancreatic Cancer
by: Nicholas D. Nguyen, et al.
Published: (2021-09-01)

The role of circadian clock-controlled mitochondrial dynamics in diabetic cardiomyopathy
by: Zhenshuai Jin, et al.
Published: (2023-05-01)