Evaluation of Bayesian Linear Regression models for gene set prioritization in complex diseases.

Genome-wide association studies (GWAS) provide valuable insights into the genetic architecture of complex traits, yet interpreting their results remains challenging due to the polygenic nature of most traits. Gene set analysis offers a solution by aggregating genetic variants into biologically relev...

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发表在:	PLoS Genetics
Main Authors:	Tahereh Gholipourshahraki, Zhonghao Bai, Merina Shrestha, Astrid Hjelholt, Sile Hu, Mads Kjolby, Palle Duun Rohde, Peter Sørensen
格式:	文件
语言:	英语
出版:	Public Library of Science (PLoS) 2024-11-01
在线阅读:	https://doi.org/10.1371/journal.pgen.1011463