A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of

A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n -BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on...

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Bibliographic Details
Published in:Natural Product Communications
Main Authors: Wasana Prapalert, Dammrong Santiarworn, Saisunee Liawruangrath, Boonsom Liawruangrath, Stephen G. Pyne
Format: Article
Language:English
Published: SAGE Publishing 2014-10-01
Online Access:https://doi.org/10.1177/1934578X1400901008
Description
Summary:A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n -BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on the basis of their spectroscopic data. These compounds were isolated for the first time from P. lanceolaria . The EtOAc and n -BuOH fractions also possessed significant antioxidant activity with IC 50 values of 57 and 50 μg/mL, respectively (DPPH method), whereas 1 had an IC 50 value of 23 μg/mL.
ISSN:1934-578X
1555-9475