A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of
A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n -BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on...
| Published in: | Natural Product Communications |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-10-01
|
| Online Access: | https://doi.org/10.1177/1934578X1400901008 |
| _version_ | 1875841771093622784 |
|---|---|
| author | Wasana Prapalert Dammrong Santiarworn Saisunee Liawruangrath Boonsom Liawruangrath Stephen G. Pyne |
| author_facet | Wasana Prapalert Dammrong Santiarworn Saisunee Liawruangrath Boonsom Liawruangrath Stephen G. Pyne |
| author_sort | Wasana Prapalert |
| collection | DOAJ |
| container_title | Natural Product Communications |
| description | A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n -BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on the basis of their spectroscopic data. These compounds were isolated for the first time from P. lanceolaria . The EtOAc and n -BuOH fractions also possessed significant antioxidant activity with IC 50 values of 57 and 50 μg/mL, respectively (DPPH method), whereas 1 had an IC 50 value of 23 μg/mL. |
| format | Article |
| id | doaj-art-e37b7a09c29e4e668151a6ebcc457d79 |
| institution | Directory of Open Access Journals |
| issn | 1934-578X 1555-9475 |
| language | English |
| publishDate | 2014-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| spelling | doaj-art-e37b7a09c29e4e668151a6ebcc457d792026-04-17T20:16:12ZengSAGE PublishingNatural Product Communications1934-578X1555-94752014-10-01910.1177/1934578X1400901008A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of Wasana Prapalert0Dammrong Santiarworn1Saisunee Liawruangrath2Boonsom Liawruangrath3Stephen G. Pyne4 Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200 Thailand Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200 Thailand Material Science Research Center and Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200 Thailand Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200 Thailand School of Chemistry, University of Wollongong, Wollongong, NSW, 2522 AustraliaA new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n -BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on the basis of their spectroscopic data. These compounds were isolated for the first time from P. lanceolaria . The EtOAc and n -BuOH fractions also possessed significant antioxidant activity with IC 50 values of 57 and 50 μg/mL, respectively (DPPH method), whereas 1 had an IC 50 value of 23 μg/mL.https://doi.org/10.1177/1934578X1400901008 |
| spellingShingle | Wasana Prapalert Dammrong Santiarworn Saisunee Liawruangrath Boonsom Liawruangrath Stephen G. Pyne A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of |
| title | A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of |
| title_full | A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of |
| title_fullStr | A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of |
| title_full_unstemmed | A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of |
| title_short | A New 1,6-Benzoxazocine-5-one Alkaloid isolated from the Aerial Parts of |
| title_sort | new 1 6 benzoxazocine 5 one alkaloid isolated from the aerial parts of |
| url | https://doi.org/10.1177/1934578X1400901008 |
| work_keys_str_mv | AT wasanaprapalert anew16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT dammrongsantiarworn anew16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT saisuneeliawruangrath anew16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT boonsomliawruangrath anew16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT stephengpyne anew16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT wasanaprapalert new16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT dammrongsantiarworn new16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT saisuneeliawruangrath new16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT boonsomliawruangrath new16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof AT stephengpyne new16benzoxazocine5onealkaloidisolatedfromtheaerialpartsof |