Interleukin-27 Enforces Regulatory T Cell Functions to Prevent Graft-versus-Host Disease

Graft-versus-host disease (GvHD) remains a significant complication of allogeneic hematopoietic cell transplantation (HCT), associated with significant morbidity and mortality. GvHD is characterized by dysregulated immune responses and resulting tissue damage of target organs. Recent investigations...

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Bibliographic Details
Published in:	Frontiers in Immunology
Main Authors:	Hongnga T. Le, Karen Keslar, Quang Tam Nguyen, Bruce R. Blazar, Betty K. Hamilton, Booki Min
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-02-01
Subjects:	adoptive transfer GvHD IL-27 regulatory T cell xenogeneic GvHD transplantation
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00181/full

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