DciA is an ancestral replicative helicase operator essential for bacterial replication initiation

DNA replication requires the loading of the replicative helicase onto the DNA molecule; in bacteria this was believed to be solely accomplished by DnaC and DnaI. Here the authors identify DciA as an ancestral and still widely distributed replicative helicase loader.

Bibliographic Details
Published in:Nature Communications
Main Authors: Pierre Brézellec, Isabelle Vallet-Gely, Christophe Possoz, Sophie Quevillon-Cheruel, Jean-Luc Ferat
Format: Article
Language:English
Published: Nature Portfolio 2016-11-01
Online Access:https://doi.org/10.1038/ncomms13271
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author Pierre Brézellec
Isabelle Vallet-Gely
Christophe Possoz
Sophie Quevillon-Cheruel
Jean-Luc Ferat
author_facet Pierre Brézellec
Isabelle Vallet-Gely
Christophe Possoz
Sophie Quevillon-Cheruel
Jean-Luc Ferat
author_sort Pierre Brézellec
collection DOAJ
container_title Nature Communications
description DNA replication requires the loading of the replicative helicase onto the DNA molecule; in bacteria this was believed to be solely accomplished by DnaC and DnaI. Here the authors identify DciA as an ancestral and still widely distributed replicative helicase loader.
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spelling doaj-art-e3892538e96845709c4a3f9500a758032025-08-19T19:14:16ZengNature PortfolioNature Communications2041-17232016-11-01711710.1038/ncomms13271DciA is an ancestral replicative helicase operator essential for bacterial replication initiationPierre Brézellec0Isabelle Vallet-Gely1Christophe Possoz2Sophie Quevillon-Cheruel3Jean-Luc Ferat4Universite de Versailles Saint-QuentinInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris‐Sud, Université Paris‐SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris‐Sud, Université Paris‐SaclayInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris‐Sud, Université Paris‐SaclayUniversite de Versailles Saint-QuentinDNA replication requires the loading of the replicative helicase onto the DNA molecule; in bacteria this was believed to be solely accomplished by DnaC and DnaI. Here the authors identify DciA as an ancestral and still widely distributed replicative helicase loader.https://doi.org/10.1038/ncomms13271
spellingShingle Pierre Brézellec
Isabelle Vallet-Gely
Christophe Possoz
Sophie Quevillon-Cheruel
Jean-Luc Ferat
DciA is an ancestral replicative helicase operator essential for bacterial replication initiation
title DciA is an ancestral replicative helicase operator essential for bacterial replication initiation
title_full DciA is an ancestral replicative helicase operator essential for bacterial replication initiation
title_fullStr DciA is an ancestral replicative helicase operator essential for bacterial replication initiation
title_full_unstemmed DciA is an ancestral replicative helicase operator essential for bacterial replication initiation
title_short DciA is an ancestral replicative helicase operator essential for bacterial replication initiation
title_sort dcia is an ancestral replicative helicase operator essential for bacterial replication initiation
url https://doi.org/10.1038/ncomms13271
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