From Bench to Chairside: Collagen Scaffolds in Combination with Mesenchymal Stromal Cells for Gingival Augmentation

<b>Background/Objectives:</b> Gingival tissue deficiencies present significant treatment challenges. We investigated three xenogeneic collagen scaffolds—Fibro-Gide, FibroMATRIX, and Mucoderm—with and without human gingival MSCs for soft tissue augmentation. <b>Methods:</b> Th...

Full description

Bibliographic Details
Published in:	Dentistry Journal
Main Authors:	Polina Koteneva, Nastasia Kosheleva, Alexey Fayzullin, Yana Khristidis, Egor Bunin, Yuri Efremov, Diana Zhukova, Sergey Tkachev, Aida Kulova, Timur Rasulov, Anna Vedyaeva, Tatiana Brailovskaya, Peter Timashev
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	gingiva soft tissue augmentation angiogenesis vascularization MSC mesenchymal stromal cells xenogenic materials
Online Access:	https://www.mdpi.com/2304-6767/13/10/460

Similar Items

Review of methodology and materials using for building of gum soft tissues
by: Svetlana V. Tarasenko, et al.
Published: (2019-04-01)

Mesenchymal Stromal Cells Enhance Vascularization and Epithelialization within 7 Days after Gingival Augmentation with Collagen Matrices in Rabbits
by: Anatoliy Kulakov, et al.
Published: (2021-09-01)

Local, systemic and immunologic safety comparison between xenogeneic equine umbilical cord mesenchymal stem cells, allogeneic canine adipose mesenchymal stem cells and placebo: a randomized controlled trial
by: Eva Punzón, et al.
Published: (2023-05-01)

Augmentation the width of a keratinized attached gingiva in patients with dental implantation
by: T. V. Brailovskaya, et al.
Published: (2018-12-01)

Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System
by: Miguel de Almeida Fuzeta, et al.
Published: (2020-11-01)

Xenogenic testicular antigens for induction of antitumor response
by: A. B. Dorzhieva, et al.
Published: (2025-06-01)

Comparative assessment of gingival thickness in pigmented and nonpigmented gingiva
by: Radhika Bharamappa, et al.
Published: (2013-01-01)

MANUFACTURING TECHNIQUE OF METAL CERAMIC RESTORATION WITH IMPLANT-ABUTMENT AT GINGIVAL RESORPTION CASE
by: Galih Paramarta, et al.
Published: (2019-07-01)

Gingival Swelling; Surprisingly Actinomycosis!
by: Rashmi G. Sawant, et al.
Published: (2023-06-01)

Fixation of free gingival grafts with cyanoacrylate glues: A histomorphometric and immunohistochemical study
by: Dayrine Silveira de Paula, et al.
Published: (2021-12-01)

STUDY OF PHARMACOLOGICAL ACTIVITY IN SUBLIMATED CULTURE LIQUID OF ALLOGENIC, XENOGENEIC HEPATOCYTES AND FIBROBLASTS FOR THE CORRECTION OF LIVER DAMAGES IN CARBON TETRACHLORIDE INTOXICATION
by: Marina Razumova, et al.
Published: (2017-12-01)

Various Methods for Measuring Gingival Thickness – A Comparative Analysis of Three Different Methodologies
by: Ankita Pati, et al.
Published: (2024-12-01)

Aesthetic Perception about Gingival Display on Maxillary Incisor Inclination among Saudi Dentists, Orthodontist and Lay Persons
by: Al Hassan Alyami, et al.
Published: (2018-07-01)

Clinical evaluation of the effect of gingival thickness on increasing the width of keratinized and attached gingiva with and without preserving periosteum in an animal study
by: Saeedeh Ebrahimi, et al.
Published: (2017-07-01)

The influence of gingival exposure on smile attractiveness
by: Azodo CC, et al.
Published: (2018-02-01)

Use of the 3D collagen matrix FibroMATRIX for the regeneration of soft tissues of the oral cavity in the treatment of Miller class I gingival recessions
by: R. R. Farkhshatova, et al.
Published: (2020-10-01)

Comparative analysis of hemodynamic characteristics of the biological xenogenic pericardial prosthesis MEDINGE-BIO with “easy change” system and the xenogenic aortic prosthesis Hancock II after aortic valve replacement
by: K. A. Petlin, et al.
Published: (2021-09-01)

Impact of gingival pigmentation on laypersons’ perception of smile aesthetics: an observational study
by: Preethi Raj, et al.
Published: (2025-01-01)

Influence of diltiazem in combination with a sucrose-rich diet on gingival alterations in rats
by: Fernanda Oliveira Bello Corrêa, et al.
Published: (2009-03-01)

The use of xenogenic testicular antigens for induction of antitumor reactions
by: G. V. Seledtsova, et al.
Published: (2024-01-01)

Generation of mouse and rat xenogeneic ovaries in vitro for production of mouse oocyte
by: Si Won Jang, et al.
Published: (2024-12-01)

Characteristics of adaptive immune effectors involved in the secondary xenogeneic immune response to human melanoma cells
by: N. A. Persiyantseva, et al.
Published: (2023-12-01)

Gingival Zenith Variations in Maxillary Anterior Teeth Across Age and Gender in the Pakistani Population
by: Alina Shahiryar, et al.
Published: (2025-04-01)

Efficacy of Triphala and Chlorhexidine Mouthwashes on Gingival Inflammation and Dental Plaque in Children: A Systematic Review
by: Anuja Singaraju, et al.
Published: (2024-11-01)

Relationship of hemoglobin levels and distribution and severity of gingival melanin pigmentation: An exploratory cross-sectional study
by: Riya Achamma Daniel, et al.
Published: (2024-11-01)

Primary isolated gingival tuberculosis
by: Gabriel Rodrigues, et al.

A comprehensive analysis of gingival phenotype: interaction and relationship between gingival and tooth morphometric parameters
by: Sude Yildirim Bolat, et al.
Published: (2025-09-01)

Double papilla flap technique for dual purpose
by: P Mohan Kumar, et al.
Published: (2012-01-01)

Postoperative Outcomes in Gingival Re-exposure
by: Wisam Rasool Jalaawi, et al.
Published: (2025-09-01)

Gingival thickness: effects on gingival wound healing
by: Kalia Theodorou, et al.
Published: (2025-03-01)

Use of Mucograft Collagen Matrix® versus Free Gingival Graft to Augment Keratinized Tissue Around Teeth: A Randomized Controlled Clinical Trial
by: Amirreza Rokn, et al.
Published: (2020-08-01)

Biomarker research: From bench to publication…but gasping to reach chairside
by: Ashish Kumar
Published: (2023-01-01)

Diagnosis and treatment of a rare case of tubercular gingival enlargement
by: Tanvi Phull, et al.
Published: (2024-01-01)

Management of inadequate width of attached gingiva using mucograft
by: Paladugu Devi Navya, et al.
Published: (2022-01-01)

Lead precipitation on the gingival tissue of Iraqi workers in some fuel stations in Baghdad
by: Dunia Wadeea Sabea
Published: (2023-01-01)

Actinomyces-associated lesions located in the gingiva: Case report of rare gingival lesions
by: Buket Acar, et al.
Published: (2017-01-01)

Long-term results of aortic valve replacement with xenogenic pericardial stentless prosthesis BioLAB KB/A
by: S. I. Babenko, et al.
Published: (2020-12-01)

Pathophysiology and preclinical relevance of experimental graft-versus-host disease in humanized mice
by: Grégory Ehx, et al.
Published: (2024-11-01)

A state of the “heart”: application of bioengineered materials for cardiac surgery
by: A. A. Sokol, et al.
Published: (2020-09-01)

Radiation cross-linked collagen scaffolds facilitate root coverage and keratinized gingival regeneration
by: Hongwei Li, et al.
Published: (2025-09-01)