Necrotic cardiac myocytes skew macrophage polarization towards a classically activated phenotype.

Necrotic and dying cells release damage-associated molecular patterns (DAMPs) that can initiate sterile inflammatory responses in the heart. Although macrophages are essential for myocardial repair and regeneration, the effect of DAMPs on macrophage activation remains unclear. To address this gap in...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS ONE
المؤلفون الرئيسيون: Wenlong Jiang, Luigi Adamo, Kenji Lim, Scot J Matkovich, Sarah Evans, Cibele Rocha-Resende, Douglas L Mann
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Public Library of Science (PLoS) 2023-01-01
الوصول للمادة أونلاين:https://doi.org/10.1371/journal.pone.0282921