Retinoid X receptor γ interacts with peroxisome proliferator-activated receptor-γ to promote browning during adipose tissue differentiation
Obesity and type 2 diabetes mellitus are global public health challenges. Activating thermogenic adipose tissues, such as brown adipose tissue and beige adipose tissue, could be a promising strategy to combat obesity and consequently obesity-related diabetes. Both peroxisome proliferator-activated r...
| Published in: | Adipocyte |
|---|---|
| Main Authors: | Defei Chen, Saed Woraikat, Xiong Guo, Fuyu Yang, Chenglin Tang, Fan He, Kun Qian |
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21623945.2025.2548780 |
Similar Items
Naringenin, a citrus flavanone, enhances browning and brown adipogenesis: Role of peroxisome proliferator-activated receptor gamma
by: Jiyoung Bae, et al.
Published: (2022-11-01)
by: Jiyoung Bae, et al.
Published: (2022-11-01)
SIRT7 Inhibits Adipose Tissue Browning Through Deacetylation of PPARγ2 at K382
by: Avizit Das, et al.
Published: (2026-06-01)
by: Avizit Das, et al.
Published: (2026-06-01)
Ups and downs: The PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis
by: Dongliang Fang, et al.
Published: (2022-01-01)
by: Dongliang Fang, et al.
Published: (2022-01-01)
Celastrol Stabilizes Glycolipid Metabolism in Hepatic Steatosis by Binding and Regulating the Peroxisome Proliferator-Activated Receptor γ Signaling Pathway
by: Mingzhu Luo, et al.
Published: (2024-01-01)
by: Mingzhu Luo, et al.
Published: (2024-01-01)
Nuclear Respiratory Factor 1 Negatively Regulates the P1 Promoter of the Peroxisome Proliferator-Activated Receptor-γ Gene and Inhibits Chicken Adipogenesis
by: Tingting Cui, et al.
Published: (2018-12-01)
by: Tingting Cui, et al.
Published: (2018-12-01)
Peroxisome proliferator-activated receptor gamma modulation and lipogenic response in adipocytes of small-for-gestational age offspring
by: Yee Jennifer K, et al.
Published: (2012-06-01)
by: Yee Jennifer K, et al.
Published: (2012-06-01)
Brown Adipogenic Reprogramming Induced by a Small Molecule
by: Baoming Nie, et al.
Published: (2017-01-01)
by: Baoming Nie, et al.
Published: (2017-01-01)
Enhanced 3T3-L1 Differentiation into Adipocytes by Pioglitazone Pharmacological Activation of Peroxisome Proliferator Activated Receptor-Gamma (PPAR-γ)
by: Catarina Teixeira, et al.
Published: (2022-05-01)
by: Catarina Teixeira, et al.
Published: (2022-05-01)
Development of an adipocyte differentiation protocol using 3T3-L1 cells for the investigation of the browning process: identification of the PPAR-γ agonist rosiglitazone as a browning reference drug
by: Lorenzo Flori, et al.
Published: (2025-04-01)
by: Lorenzo Flori, et al.
Published: (2025-04-01)
BADGE, a synthetic antagonist for PPARγ, prevents steroid-related osteonecrosis in a rabbit model
by: Na Yuan, et al.
Published: (2018-04-01)
by: Na Yuan, et al.
Published: (2018-04-01)
Microsecond MD Simulations to Explore the Structural and Energetic Differences between the Human RXRα-PPARγ vs. RXRα-PPARγ-DNA
by: Faizul Azam, et al.
Published: (2022-09-01)
by: Faizul Azam, et al.
Published: (2022-09-01)
Naringenin and β-carotene convert human white adipocytes to a beige phenotype and elevate hormone- stimulated lipolysis
by: Ann A. Coulter, et al.
Published: (2023-04-01)
by: Ann A. Coulter, et al.
Published: (2023-04-01)
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model
by: Dandan Zhao, et al.
Published: (2021-03-01)
by: Dandan Zhao, et al.
Published: (2021-03-01)
Adipogenic and osteogenic effects of OBS and synergistic action with PFOS via PPARγ–RXRα heterodimers
by: Hui Qin, et al.
Published: (2024-01-01)
by: Hui Qin, et al.
Published: (2024-01-01)
Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue
by: Jacob Ardenkjær-Skinnerup, et al.
Published: (2024-07-01)
by: Jacob Ardenkjær-Skinnerup, et al.
Published: (2024-07-01)
FGF11 influences 3T3‐L1 preadipocyte differentiation by modulating the expression of PPARγ regulators
by: Kyeong Won Lee, et al.
Published: (2019-04-01)
by: Kyeong Won Lee, et al.
Published: (2019-04-01)
The Tumor Suppressor Par-4 Regulates Adipogenesis by Transcriptional Repression of PPARγ
by: James Sledziona, et al.
Published: (2024-09-01)
by: James Sledziona, et al.
Published: (2024-09-01)
PPAR-γ Modulators as Current and Potential Cancer Treatments
by: Tiange Chi, et al.
Published: (2021-09-01)
by: Tiange Chi, et al.
Published: (2021-09-01)
Senescent T Cell Induces Brown Adipose Tissue “Whitening” Via Secreting IFN-γ
by: Xiao-Xi Pan, et al.
Published: (2021-03-01)
by: Xiao-Xi Pan, et al.
Published: (2021-03-01)
The autophagic regulation of rosiglitazone-promoted adipocyte browning
by: Yue Li, et al.
Published: (2024-06-01)
by: Yue Li, et al.
Published: (2024-06-01)
Deletion of Spinophilin Promotes White Adipocyte Browning
by: Wenyu Gou, et al.
Published: (2023-01-01)
by: Wenyu Gou, et al.
Published: (2023-01-01)
Modulation of retinoid-X-receptors differentially regulates expression of apolipoprotein genes apoc1 and apoeb by zebrafish microglia
by: Whitney A. Thiel, et al.
Published: (2022-01-01)
by: Whitney A. Thiel, et al.
Published: (2022-01-01)
Assessment of total, ligand-induced peroxisome proliferator activated receptor γ ligand activity in serum
by: Lariah Edwards, et al.
Published: (2019-05-01)
by: Lariah Edwards, et al.
Published: (2019-05-01)
Phenolic Compounds Inhibit 3T3-L1 Adipogenesis Depending on the Stage of Differentiation and Their Binding Affinity to PPARγ
by: Paula Aranaz, et al.
Published: (2019-03-01)
by: Paula Aranaz, et al.
Published: (2019-03-01)
Electroacupuncture Regulates Inguinal White Adipose Tissue Browning by Promoting Sirtuin-1-Dependent PPARγ Deacetylation and Mitochondrial Biogenesis
by: Qianqian Tang, et al.
Published: (2021-01-01)
by: Qianqian Tang, et al.
Published: (2021-01-01)
Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 gene on lipid profile and adipokines levels in obese subjects
by: Becer E, et al.
Published: (2017-06-01)
by: Becer E, et al.
Published: (2017-06-01)
Cytoplasmic Colocalization of RXRα and PPARγ as an Independent Negative Prognosticator for Breast Cancer Patients
by: Wanting Shao, et al.
Published: (2022-04-01)
by: Wanting Shao, et al.
Published: (2022-04-01)
microRNA-27a-3p but Not -5p Is a Crucial Mediator of Human Adipogenesis
by: Hang Wu, et al.
Published: (2021-11-01)
by: Hang Wu, et al.
Published: (2021-11-01)
Perfluorooctanoate (PFOA) cell-autonomously promotes thermogenic and adipogenic differentiation of brown and white adipocytes
by: Patrícia Reckziegel, et al.
Published: (2024-02-01)
by: Patrícia Reckziegel, et al.
Published: (2024-02-01)
Control of brown adipose tissue glucose and lipid metabolism by PPARγ
by: William T. Festuccia, et al.
Published: (2011-12-01)
by: William T. Festuccia, et al.
Published: (2011-12-01)
Modulation of adiposity and adipocyte inflammation by methanol extracts of Alpinia calcarata leaf in high-fat-diet induced-obese mice: Involvement of COX-2 and PPAR-γ
by: Imtiaz Ahmad, et al.
Published: (2025-01-01)
by: Imtiaz Ahmad, et al.
Published: (2025-01-01)
The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ
by: Xiaofang Luo, et al.
Published: (2025-04-01)
by: Xiaofang Luo, et al.
Published: (2025-04-01)
Polyphyllin I exerts anti-hepatocellular carcinoma activity by targeting ZBTB16 to activate the PPARγ/RXRα signaling pathway
by: Lu shan, et al.
Published: (2024-08-01)
by: Lu shan, et al.
Published: (2024-08-01)
FTO Intronic SNP Strongly Influences Human Neck Adipocyte Browning Determined by Tissue and PPARγ Specific Regulation: A Transcriptome Analysis
by: Beáta B. Tóth, et al.
Published: (2020-04-01)
by: Beáta B. Tóth, et al.
Published: (2020-04-01)
Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation
by: Sen‐bo Yan, et al.
Published: (2023-12-01)
by: Sen‐bo Yan, et al.
Published: (2023-12-01)
Tumor necrosis factor-α reduces adiponectin production by decreasing transcriptional activity of peroxisome proliferator-activated receptor-γ in calf adipocytes
by: Hao Yu, et al.
Published: (2023-07-01)
by: Hao Yu, et al.
Published: (2023-07-01)
Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C
by: Lizcano Fernando, et al.
Published: (2011-01-01)
by: Lizcano Fernando, et al.
Published: (2011-01-01)
The Immunotherapeutic Effects of Pentoxifylline in Type 1 Diabetic Mice and its Effects on Expressions of Peroxisome proliferator-activated receptor gamma (PPARγ) gene
by: F Malekifar, et al.
Published: (2015-05-01)
by: F Malekifar, et al.
Published: (2015-05-01)
GIPR expression is induced by thiazolidinediones in a PPARγ-independent manner and repressed by obesogenic stimuli
by: Simona Cataldi, et al.
Published: (2023-06-01)
by: Simona Cataldi, et al.
Published: (2023-06-01)
Protopanaxadiol-Enriched Rice Exerted Antiadipogenic Activity during 3T3-L1 Differentiation and Anti-Inflammatory Activity in 3T3-L1 Adipocytes
by: Chaiwat Monmai, et al.
Published: (2023-08-01)
by: Chaiwat Monmai, et al.
Published: (2023-08-01)
Similar Items
-
Naringenin, a citrus flavanone, enhances browning and brown adipogenesis: Role of peroxisome proliferator-activated receptor gamma
by: Jiyoung Bae, et al.
Published: (2022-11-01) -
SIRT7 Inhibits Adipose Tissue Browning Through Deacetylation of PPARγ2 at K382
by: Avizit Das, et al.
Published: (2026-06-01) -
Ups and downs: The PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis
by: Dongliang Fang, et al.
Published: (2022-01-01) -
Celastrol Stabilizes Glycolipid Metabolism in Hepatic Steatosis by Binding and Regulating the Peroxisome Proliferator-Activated Receptor γ Signaling Pathway
by: Mingzhu Luo, et al.
Published: (2024-01-01) -
Nuclear Respiratory Factor 1 Negatively Regulates the P1 Promoter of the Peroxisome Proliferator-Activated Receptor-γ Gene and Inhibits Chicken Adipogenesis
by: Tingting Cui, et al.
Published: (2018-12-01)
