Structure-Activity Relationship Studies Based on 3D-QSAR CoMFA/CoMSIA for Thieno-Pyrimidine Derivatives as Triple Negative Breast Cancer Inhibitors

Triple-negative breast cancer (TNBC) is defined as a kind of breast cancer that lacks estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptors (HER2). This cancer accounts for 10–15% of all breast cancers and has the features of high invasiveness and metastat...

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Bibliographic Details
Published in:	Molecules
Main Authors:	Jin-Hee Kim, Jin-Hyun Jeong
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	TNBC VEGFR3 thieno-pyrimidine derivatives 3D-QSAR CoMFA CoMSIA
Online Access:	https://www.mdpi.com/1420-3049/27/22/7974

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