Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells

Abstract Background A new strategy, particularly a novel combination, for immunotherapy in microsatellite stable metastatic colorectal cancer (mCRC) treatment needs to be formulated. Studies on the interferon-γ (IFN-γ)/ Janus kinase (JAK)/ signal transducer and activator of transcription (STAT)1 pat...

書目詳細資料
發表在:	Journal of Biomedical Science
Main Authors:	Yi-Hsin Liang, Kuo-Hsing Chen, Jia-Huei Tsai, Yung-Ming Cheng, Chang-Cheng Lee, Chiu-Hwa Kao, Kuang-Yu Chan, Yeh-Ting Chen, Wen-Ling Hsu, Kun-Huei Yeh
格式:	Article
語言:	英语
出版:	BMC 2021-11-01
主題:	Colorectal cancer Major histocompatibility complex (MHC) class I Proteasome inhibitors STAT1 Tumor infiltrating lymphocytes (TILs) Interferon-γ (IFN-γ)
在線閱讀:	https://doi.org/10.1186/s12929-021-00769-9

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