Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα‐FGF21 Axis

The fatty acid desaturase 1 (FADS1), also known as delta‐5 desaturase (D5D), is one of the rate‐limiting enzymes involved in the desaturation and elongation cascade of polyunsaturated fatty acids (PUFAs) to generate long‐chain PUFAs (LC‐PUFAs). Reduced function of D5D and decreased hepatic FADS1 exp...

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Bibliographic Details
Published in:	Hepatology Communications
Main Authors:	Shaminie Athinarayanan, Yang‐Yi Fan, Xiaokun Wang, Evelyn Callaway, Defeng Cai, Naga Chalasani, Robert S. Chapkin, Wanqing Liu
Format:	Article
Language:	English
Published:	Wolters Kluwer Health/LWW 2021-03-01
Online Access:	https://doi.org/10.1002/hep4.1629

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