A One-Pot Divergent Sequence to Pyrazole and Quinoline Derivatives
The hydroxy-pyrazole and 3-hydroxy-oxindole motifs have been utilised in several pharma and agrochemical leads but are distinctly underrepresented in the scientific literature due to the limited routes of preparation. We have developed a one-pot procedure for their synthesis starting from simple isa...
| 發表在: | Molecules |
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| Main Authors: | , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
MDPI AG
2020-05-01
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| 主題: | |
| 在線閱讀: | https://www.mdpi.com/1420-3049/25/9/2160 |
| 總結: | The hydroxy-pyrazole and 3-hydroxy-oxindole motifs have been utilised in several pharma and agrochemical leads but are distinctly underrepresented in the scientific literature due to the limited routes of preparation. We have developed a one-pot procedure for their synthesis starting from simple isatins. The method employs cheap and easy-to-handle building blocks and allows easy isolation. |
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| ISSN: | 1420-3049 |