Report from the 5th cardiovascular outcome trial (CVOT) summit

Abstract The 5th Cardiovascular Outcome Trial (CVOT) Summit was held in Munich on October 24th–25th, 2019. As in previous years, this summit served as a reference meeting for in-depth discussions on the topic of recently completed and presented CVOTs. This year, focus was placed on the CVOTs CAROLIN...

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Bibliographic Details
Published in:Cardiovascular Diabetology
Main Authors: Oliver Schnell, Eberhard Standl, Xavier Cos, Hiddo JL Heerspink, Baruch Itzhak, Nebojsa Lalic, Michael Nauck, Antonio Ceriello
Format: Article
Language:English
Published: BMC 2020-04-01
Subjects:
Cardiovascular risk
Diabetes
CVOT
CAROLINA
CREDENCE
DAPA-HF
Online Access:http://link.springer.com/article/10.1186/s12933-020-01022-7
Description
Summary:Abstract The 5th Cardiovascular Outcome Trial (CVOT) Summit was held in Munich on October 24th–25th, 2019. As in previous years, this summit served as a reference meeting for in-depth discussions on the topic of recently completed and presented CVOTs. This year, focus was placed on the CVOTs CAROLINA, CREDENCE, DAPA-HF, REWIND, and PIONEER-6. Trial implications for diabetes management and the impact on new treatment algorithms were highlighted for diabetologists, cardiologists, endocrinologists, nephrologists, and general practitioners. Discussions evolved from CVOTs to additional therapy options for heart failure (ARNI), knowledge gained for the treatment and prevention of heart failure and diabetic kidney disease in populations with and without diabetes, particularly using SGLT-2 inhibitors and GLP-1 receptor agonists. Furthermore, the ever increasing impact of CVOTs and substances tested for primary prevention and primary care was discussed. The 6th Cardiovascular Outcome Trial Summit will be held in Munich on October 29th–30th, 2020 ( https://www.cvot.org ).
ISSN:1475-2840

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