Sustained Release Therapies with the Prostaglandin Analogues Intracameral Implants

Abstract The travoprost intracameral implant was recently approved by the US Food and Drug Administration for sustained release medical treatment of open-angle glaucoma in the USA. The approval represents a substantial and progressive step forward in the area of sustained-release glaucoma therapy. T...

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Bibliographic Details
Published in:Ophthalmology and Therapy
Main Authors: Abdelrahman M. Elhusseiny, Ahmad A. Aref
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-05-01
Subjects:
Online Access:https://doi.org/10.1007/s40123-024-00965-4
Description
Summary:Abstract The travoprost intracameral implant was recently approved by the US Food and Drug Administration for sustained release medical treatment of open-angle glaucoma in the USA. The approval represents a substantial and progressive step forward in the area of sustained-release glaucoma therapy. Topical intraocular pressure-lowering medications for the treatment of glaucoma are faced with a host of challenges for long-term and usually lifelong care. A changing paradigm in glaucoma management involves first-line interventions with laser modalities, micro-invasive surgeries, and sustained-release treatment platforms. Future needs in the area of sustained-release therapy include a non-prostaglandin drug delivery platform and longer-term treatments that do not require surgical reintervention.
ISSN:2193-8245
2193-6528