| Summary: | Abstract Objective To evaluate the clinical efficacy of vestibular incision subperiosteal tunnel access (VISTA) combined with various biomaterials or graft substitutes in the treatment of gingival recession. Methods A systematic search was conducted in five English databases and four Chinese databases. Data analysis was performed using STATA 16.0 software. Results A total of 14 literature were included, involving 226 patients with Miller class I or II gingival recession and 526 affected teeth, including 10 cases of single gingival recession patients. The meta-analysis results showed that after treatment with VISTA combined with various biomaterials or graft substitutes, the average gingival recession depth (GRD) of patients decreased by 1.36 [MD = -1.36, 95% CI: -1.84, -0.89, Z=-5.604, P < 0.001]; the average complete root coverage (CRC) was 58% [CRC% = 0.58, 95% CI: 0.49, 0.68, Z = 11.684, P < 0.001]; the average keratinized gingiva (KG) increased by 1.32 [MD = 1.32, 95% CI: 0.92, 1.72, Z = 6.416, P < 0.001]; the average keratinized tissue thickness (KTT) increased by 0.46 [MD = 0.46, 95% CI: 0.27, 0.65, Z = 4.765, P < 0.001]; the average probing depth (PD) decreased by 0.18 [MD=-0.18, 95% CI: -0.34, -0.02, Z=-2.259, P = 0.024]; and the average clinical attachment level (CAL) decreased by 2.14 [MD=-2.14, 95% CI:-2.78, -1.51, Z=-6.611, P < 0.001]. Conclusion VISTA combined with various biomaterials or graft substitutes is significantly effective in treating Miller class I or II gingival recession. These conclusions provide relevant references for the clinical selection of VISTA treatment methods.
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