| Summary: | Objectives: Orthognathic surgery is popular and provides patients with improved aesthetics and functionality. The procedure is considered safe and predictable. Possible complications do exist and can be life-threatening. The aim of this study is to assess the prevalence of intra- and post-operative complications, and to define possible correlations between diagnoses. Study Design: Medical records of 103 patients who underwent orthognathic surgery in a 4.5-year period (2013–2017), at the Baruch Padeh “Tzafon” Medical Center in Poriya (PMC), Israel, were retrospectively collected. The data were analyzed for descriptive statistics and non-parametrical tests. Results: In total, there were 56 complications in 45 patients (43.7% probability of complication per patient). Major complication occurred in only one case (1%), moderate complications appeared in 8.7% of the cases, while the most prevalent minor complications were temporary nerve injury and hardware issues (17.5% and 15.5%, respectively). Statistical analysis revealed that bi-max surgery has significantly higher (OR 1.34, CI 99% 1.05–1.69, <i>p</i> = 0.019) prevalence of complications than one-jaw surgery, as did skeletal class II patients (OR 2.75, CI 99% 2.25–3.35, <i>p</i> = 0.022), as compared to skeletal class III patients. Conclusions: Serious complications seem to be rare in orthognathic surgery at PMC.
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