Generation of a TLR2 knockout human induced pluripotent stem cell line using CRISPR/Cas9

The TLR family plays a fundamental function in the recognition of pathogens and activation of innate immunity. TLR2 is a membrane protein that is expressed on the surface of certain cells and recognizes foreign substances; it initiates a cascade of innate immune responses. TLR2 recognizes many bacte...

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Bibliographic Details
Published in:Stem Cell Research
Main Authors: Hyeong-jun Han, Jung-Hyun Kim
Format: Article
Language:English
Published: Elsevier 2021-12-01
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121004256