Noise-aided logic in an electronic analog of synthetic genetic networks.

• Published in: PLoS ONE
• Main Authors: Edward H Hellen, Syamal K Dana, Jürgen Kurths, Eli Kehler, Sudeshna Sinha
• Format: Article
• Language: English
• Published: Public Library of Science (PLoS) 2013-01-01
• Online Access: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0076032&type=printable

We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and numerical prediction, with the circuit allowing for robust logic operations in an optimal window of noise. Namely, the input-output characteristics of a logic gate is reproduced faithfully under moderate noise, which is a manifestation of the phenomenon known as Logical Stochastic Resonance. The two dynamical variables in the system yield complementary logic behaviour simultaneously. The system is easily morphed from AND/NAND to OR/NOR logic.