Sodium Malonate Inhibits the AcrAB-TolC Multidrug Efflux Pump of <i>Escherichia coli</i> and Increases Antibiotic Efficacy

There is an urgent need to find novel treatments for combating multidrug-resistant bacteria. Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this problem. Therefore, using efflux pump inhibitors (EPIs) is a promising strategy to increase antibiotic efficacy. Howe...

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Bibliographic Details
Published in:	Pathogens
Main Authors:	Allea Cauilan, Cristian Ruiz
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	malonate sodium malonate malonic acid AcrAB-TolC multidrug efflux pump efflux pump inhibitor
Online Access:	https://www.mdpi.com/2076-0817/11/12/1409

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