Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use

Toshimi Chiba,1,* Ting Wang,1,* Satoshi Kikuchi2,* 1Division of Internal Medicine, Department of Oral Medicine, Iwate Medical University, Morioka, Iwate, Japan; 2Department of Gastroenterology, Sanai Hospital, Morioka, Iwate, Japan*These authors contributed equally to...

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Published in:International Medical Case Reports Journal
Main Authors: Chiba T, Wang T, Kikuchi S
Format: Article
Language:English
Published: Dove Medical Press 2024-09-01
Subjects:
Online Access:https://www.dovepress.com/colonoscopic-resolution-of-melanosis-coli-after-cessation-of-senna-lax-peer-reviewed-fulltext-article-IMCRJ
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author Chiba T
Wang T
Kikuchi S
author_facet Chiba T
Wang T
Kikuchi S
author_sort Chiba T
collection DOAJ
container_title International Medical Case Reports Journal
description Toshimi Chiba,1,* Ting Wang,1,* Satoshi Kikuchi2,* 1Division of Internal Medicine, Department of Oral Medicine, Iwate Medical University, Morioka, Iwate, Japan; 2Department of Gastroenterology, Sanai Hospital, Morioka, Iwate, Japan*These authors contributed equally to this workCorrespondence: Toshimi Chiba, Division of Internal Medicine, Department of Oral Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan, Tel +81 19 651 5111, Fax +81 19 654 3281, Email toschiba@iwate-med.ac.jpAbstract: Melanosis coli occurs with the administration of stimulant laxatives for the relief of constipation. However, the duration of macroscopic improvement of melanosis coli after discontinuation of anthracene laxatives is not well understood. We describe the case of an 81-year-old female diagnosed with melanosis coli via colonoscopy who had been taking senna laxatives for 5 years. Seven months after cessation of senna laxatives, colonoscopy showed no melanosis coli in the colon. This impressive report describes the observation of melanosis coli with colonoscopy; 7 months after the withdrawal of senna stimulant laxatives, melanosis coli resolved.Keywords: melanosis coli, colonoscopy, discontinued, senna laxative, anthraquinone
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spelling doaj-art-e53132d3d425447c982ea760a0d46cbf2025-08-19T23:21:07ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2024-09-01Volume 1778378795606Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative UseChiba TWang TKikuchi SToshimi Chiba,1,* Ting Wang,1,* Satoshi Kikuchi2,* 1Division of Internal Medicine, Department of Oral Medicine, Iwate Medical University, Morioka, Iwate, Japan; 2Department of Gastroenterology, Sanai Hospital, Morioka, Iwate, Japan*These authors contributed equally to this workCorrespondence: Toshimi Chiba, Division of Internal Medicine, Department of Oral Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan, Tel +81 19 651 5111, Fax +81 19 654 3281, Email toschiba@iwate-med.ac.jpAbstract: Melanosis coli occurs with the administration of stimulant laxatives for the relief of constipation. However, the duration of macroscopic improvement of melanosis coli after discontinuation of anthracene laxatives is not well understood. We describe the case of an 81-year-old female diagnosed with melanosis coli via colonoscopy who had been taking senna laxatives for 5 years. Seven months after cessation of senna laxatives, colonoscopy showed no melanosis coli in the colon. This impressive report describes the observation of melanosis coli with colonoscopy; 7 months after the withdrawal of senna stimulant laxatives, melanosis coli resolved.Keywords: melanosis coli, colonoscopy, discontinued, senna laxative, anthraquinonehttps://www.dovepress.com/colonoscopic-resolution-of-melanosis-coli-after-cessation-of-senna-lax-peer-reviewed-fulltext-article-IMCRJmelanosis colicolonoscopydiscontinuedsenna laxativeanthraquinone
spellingShingle Chiba T
Wang T
Kikuchi S
Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use
melanosis coli
colonoscopy
discontinued
senna laxative
anthraquinone
title Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use
title_full Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use
title_fullStr Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use
title_full_unstemmed Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use
title_short Colonoscopic Resolution of Melanosis Coli After Cessation of Senna Laxative Use
title_sort colonoscopic resolution of melanosis coli after cessation of senna laxative use
topic melanosis coli
colonoscopy
discontinued
senna laxative
anthraquinone
url https://www.dovepress.com/colonoscopic-resolution-of-melanosis-coli-after-cessation-of-senna-lax-peer-reviewed-fulltext-article-IMCRJ
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AT kikuchis colonoscopicresolutionofmelanosiscoliaftercessationofsennalaxativeuse