Bowman layer transplantation in eyes with progressive advanced keratoconus

Purpose: to study the efficiency of Bowman layer transplantation (BLT) in corneal stroma for the treatment of progressive keratoconus (KC).Material and methods. 30 patients (30 eyes) with progressive KC stages III to IV (according to Amsler — Krumeich classification), underwent BLT into a mid-stroma...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Российский офтальмологический журнал
المؤلفون الرئيسيون: O. G. Oganesyan, V. R. Getadaryan, P. V. Makarov, A. A. Grdikanyan
التنسيق: مقال
اللغة:الروسية
منشور في: Real Time Ltd 2019-12-01
الموضوعات:
الوصول للمادة أونلاين:https://roj.igb.ru/jour/article/view/336
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author O. G. Oganesyan
V. R. Getadaryan
P. V. Makarov
A. A. Grdikanyan
author_facet O. G. Oganesyan
V. R. Getadaryan
P. V. Makarov
A. A. Grdikanyan
author_sort O. G. Oganesyan
collection DOAJ
container_title Российский офтальмологический журнал
description Purpose: to study the efficiency of Bowman layer transplantation (BLT) in corneal stroma for the treatment of progressive keratoconus (KC).Material and methods. 30 patients (30 eyes) with progressive KC stages III to IV (according to Amsler — Krumeich classification), underwent BLT into a mid-stromal pocket. At the time of surgery, the patients were 14 to 37 (averagely 26.6 ± 6.2 years). Before and after the surgery, the maximum keratometry index (Kmax) and the corneal thinnest point (CTP) values were determined. Also, we evaluated visual acuity before and after surgery in scleral contact lenses, endothelial cells density (ECD) and the depth of graft location. The indication for surgery was the refusal of corneal transplantation, progression of KC, contraindications for ultraviolet crosslinking or implantation of intracorneal ring segments based on the CTP and Kmax values. The follow-up continued 6 to 36 months (averagely, 26.6 ± 6.0 months).Results. Throughout the observation period, no intra or postoperative complications associated with BLT or deterioration of CTP, Kmax or best corrected visual acuity (BCVA) in scleral lenses were noted.Conclusions. Kmax, CTP and ECD values remaining stable during the follow-up is the evidence of a stabilizing BLT effect on the KC progression. The absence of BCVA decrease in scleral lenses indicates a functional safety of BLT.
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spelling doaj-art-e538a06763ea4e5ca2795feaf983101f2025-08-20T03:59:17ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602019-12-01124435010.21516/2072-0076-2019-12-4-43-50250Bowman layer transplantation in eyes with progressive advanced keratoconusO. G. Oganesyan0V. R. Getadaryan1P. V. Makarov2A. A. Grdikanyan3Helmholtz National Medical Research Center of Eye Diseases; A.I. Evdokimov Moscow State University of Medicine and DentistryHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesPurpose: to study the efficiency of Bowman layer transplantation (BLT) in corneal stroma for the treatment of progressive keratoconus (KC).Material and methods. 30 patients (30 eyes) with progressive KC stages III to IV (according to Amsler — Krumeich classification), underwent BLT into a mid-stromal pocket. At the time of surgery, the patients were 14 to 37 (averagely 26.6 ± 6.2 years). Before and after the surgery, the maximum keratometry index (Kmax) and the corneal thinnest point (CTP) values were determined. Also, we evaluated visual acuity before and after surgery in scleral contact lenses, endothelial cells density (ECD) and the depth of graft location. The indication for surgery was the refusal of corneal transplantation, progression of KC, contraindications for ultraviolet crosslinking or implantation of intracorneal ring segments based on the CTP and Kmax values. The follow-up continued 6 to 36 months (averagely, 26.6 ± 6.0 months).Results. Throughout the observation period, no intra or postoperative complications associated with BLT or deterioration of CTP, Kmax or best corrected visual acuity (BCVA) in scleral lenses were noted.Conclusions. Kmax, CTP and ECD values remaining stable during the follow-up is the evidence of a stabilizing BLT effect on the KC progression. The absence of BCVA decrease in scleral lenses indicates a functional safety of BLT.https://roj.igb.ru/jour/article/view/336donor corneakeratoconuskeratoplastybowman layer transplantation
spellingShingle O. G. Oganesyan
V. R. Getadaryan
P. V. Makarov
A. A. Grdikanyan
Bowman layer transplantation in eyes with progressive advanced keratoconus
donor cornea
keratoconus
keratoplasty
bowman layer transplantation
title Bowman layer transplantation in eyes with progressive advanced keratoconus
title_full Bowman layer transplantation in eyes with progressive advanced keratoconus
title_fullStr Bowman layer transplantation in eyes with progressive advanced keratoconus
title_full_unstemmed Bowman layer transplantation in eyes with progressive advanced keratoconus
title_short Bowman layer transplantation in eyes with progressive advanced keratoconus
title_sort bowman layer transplantation in eyes with progressive advanced keratoconus
topic donor cornea
keratoconus
keratoplasty
bowman layer transplantation
url https://roj.igb.ru/jour/article/view/336
work_keys_str_mv AT ogoganesyan bowmanlayertransplantationineyeswithprogressiveadvancedkeratoconus
AT vrgetadaryan bowmanlayertransplantationineyeswithprogressiveadvancedkeratoconus
AT pvmakarov bowmanlayertransplantationineyeswithprogressiveadvancedkeratoconus
AT aagrdikanyan bowmanlayertransplantationineyeswithprogressiveadvancedkeratoconus