Emerging Approaches to Profile Accessible Chromatin from Formalin-Fixed Paraffin-Embedded Sections
Nucleosomes are non-uniformly distributed across eukaryotic genomes, with stretches of ‘open’ chromatin strongly associated with transcriptionally active promoters and enhancers. Understanding chromatin accessibility patterns in normal tissue and how they are altered in pathologies can provide criti...
| 發表在: | Epigenomes |
|---|---|
| Main Authors: | Vishnu Udayakumaran Nair Sunitha Kumary, Bryan J. Venters, Karthikeyan Raman, Sagnik Sen, Pierre-Olivier Estève, Martis W. Cowles, Michael-Christopher Keogh, Sriharsa Pradhan |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
MDPI AG
2024-05-01
|
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/2075-4655/8/2/20 |
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