RT-QuIC: a highly promising diagnostic method for neurodegenerative diseases—advantages and limitations

Although it has been more than 200 years since Parkinson’s disease was described, we have not established biomarkers for its definitive diagnosis yet. Moreover, there is a similar case for the entire group of α-synucleinopathies, which are all characterized by the pathological accumulation of aggreg...

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Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	D. Koníčková, D. Hraboš, K. Menšíková, L. Tučková, M. Kaleta, M. Strnad, C. Colosimo, P. Kaňovský
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	alpha-synuclein seed amplification assays RT-QuIC Parkinson’s disease biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1578252/full