Mechanical loading due to muscle movement regulates establishment of the collagen network in the developing murine skeleton

Mechanical loading is critical for collagen network maintenance and remodelling in adult skeletal tissues, but the role of loading in collagen network formation during development is poorly understood. We test the hypothesis that mechanical loading is necessary for the onset and maturation of spatia...

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Bibliographic Details
Published in:	Royal Society Open Science
Main Authors:	Saima Ahmed, Andrew V. Rogers, Niamh C. Nowlan
Format:	Article
Language:	English
Published:	The Royal Society 2023-10-01
Subjects:	collagen I collagen II collagen VI collagen X collagen XI bioreactor
Online Access:	https://royalsocietypublishing.org/doi/10.1098/rsos.231023

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