MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum.

The frequent overexpression of CD46 in malignant tumors has provided a basis to use vaccine-lineage measles virus (MeV) as an oncolytic virotherapy platform. However, widespread measles seropositivity limits the systemic deployment of oncolytic MeV for the treatment of metastatic neoplasia. Here, we...

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Bibliographic Details
Published in:	PLoS Pathogens
Main Authors:	Miguel Ángel Muñoz-Alía, Rebecca A Nace, Alexander Tischer, Lianwen Zhang, Eugene S Bah, Matthew Auton, Stephen J Russell
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-02-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009283&type=printable

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