Issues Determining Direct Airways Hyperresponsiveness in Mice

Airways hyperresponsiveness (AHR) is frequently a primary outcome in mouse models of asthma. There are, however, a number of variables that may affect the outcome of such measurements and the interpretation of the results. This article highlights issues that should be in mind when designing experi...

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Bibliographic Details
Published in:	Frontiers in Physiology
Main Author:	Lennart Karl, Alf Lundblad
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-10-01
Subjects:	Asthma Methacholine Chloride mouse models hyperresponsiveness forced oscillation respiratory impedance
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00408/full

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