Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction

Myelination of axons facilitates rapid impulse propagation in the nervous system. The axon/myelin-unit becomes impaired in myelin-related disorders and upon normal aging. However, the molecular cause of many pathological features, including the frequently observed myelin outfoldings, remained unknow...

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Bibliographic Details

Published in:	eLife
Main Authors:	Julia Patzig, Michelle S Erwig, Stefan Tenzer, Kathrin Kusch, Payam Dibaj, Wiebke Möbius, Sandra Goebbels, Nicole Schaeren-Wiemers, Klaus-Armin Nave, Hauke B Werner
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2016-08-01
Subjects:	glial cells myelinated axons neuropathology myelin structure label-free proteomics septin cytoskeleton
Online Access:	https://elifesciences.org/articles/17119