Selective mitochondrial DNA degradation following double-strand breaks.

Mitochondrial DNA (mtDNA) can undergo double-strand breaks (DSBs), caused by defective replication, or by various endogenous or exogenous sources, such as reactive oxygen species, chemotherapeutic agents or ionizing radiations. MtDNA encodes for proteins involved in ATP production, and maintenance o...

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發表在:	PLoS ONE
Main Authors:	Amandine Moretton, Frédéric Morel, Bertil Macao, Philippe Lachaume, Layal Ishak, Mathilde Lefebvre, Isabelle Garreau-Balandier, Patrick Vernet, Maria Falkenberg, Géraldine Farge
格式:	Article
語言:	英语
出版:	Public Library of Science (PLoS) 2017-01-01
在線閱讀:	http://europepmc.org/articles/PMC5409072?pdf=render