Expression and clinical significance of ITGA3 in breast cancer
Integrin subunit Alpha 3 is essential for cell adhesion and movement, but its role in breast cancer (BC) is unclear. This study evaluated ITGA3 expression in BC and its clinical significance.
| Published in: | Open Medicine |
|---|---|
| Main Authors: | Song Huachun, Gao Meihui, Bao Zheng, Yang Yong, Chen Yang, Hao Jing |
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2025-04-01
|
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2024-1113 |
Similar Items
Immunological role and prognostic value of ITGA3 and ITGA5 in oral squamous cell carcinoma
by: Lujuan Wang, et al.
Published: (2025-08-01)
by: Lujuan Wang, et al.
Published: (2025-08-01)
MUC1 promotes cervical squamous cell carcinoma through ERK phosphorylation-mediated regulation of ITGA2/ITGA3
by: Aiqin Zhao, et al.
Published: (2024-05-01)
by: Aiqin Zhao, et al.
Published: (2024-05-01)
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer
by: Wei Tan, et al.
Published: (2024-11-01)
by: Wei Tan, et al.
Published: (2024-11-01)
PSAT1 Promotes Metastasis via p-AKT/SP1/ITGA2 Axis in Estrogen Receptor-Negative Breast Cancer Cell
by: Xingda Zhang, et al.
Published: (2024-08-01)
by: Xingda Zhang, et al.
Published: (2024-08-01)
ITGA11, a Prognostic Factor Associated with Immunity in Gastric Adenocarcinoma
by: Yang X, et al.
Published: (2024-02-01)
by: Yang X, et al.
Published: (2024-02-01)
ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis
by: Valery Adorno-Cruz, et al.
Published: (2021-07-01)
by: Valery Adorno-Cruz, et al.
Published: (2021-07-01)
A comprehensive analysis of notch signaling genes in breast cancer: Expression pattern and prognostic significance
by: Shazia Sofi, et al.
Published: (2023-07-01)
by: Shazia Sofi, et al.
Published: (2023-07-01)
ITGA5 promotes tumor angiogenesis in cervical cancer
by: Xiaohan Xu, et al.
Published: (2023-05-01)
by: Xiaohan Xu, et al.
Published: (2023-05-01)
Molecular typing of gliomas on the basis of integrin family genes and a functional study of ITGA7
by: Hongxi Han, et al.
Published: (2025-04-01)
by: Hongxi Han, et al.
Published: (2025-04-01)
FN1, FOS, and ITGA5 induce preeclampsia: Abnormal expression and methylation
by: Mei Zhao, et al.
Published: (2017-10-01)
by: Mei Zhao, et al.
Published: (2017-10-01)
Poor Prognosis of Oral Squamous Cell Carcinoma Correlates With ITGA6
by: Churen Zhang, et al.
Published: (2023-04-01)
by: Churen Zhang, et al.
Published: (2023-04-01)
ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation
by: Jiaxing Zhang, et al.
Published: (2025-02-01)
by: Jiaxing Zhang, et al.
Published: (2025-02-01)
Free or fixed state of nHAP differentially regulates hBMSC morphology and osteogenesis through the valve role of ITGA7
by: Fangyuan Bao, et al.
Published: (2022-12-01)
by: Fangyuan Bao, et al.
Published: (2022-12-01)
Thermoradiotherapy reverses proliferation, metastasis, and anoikis resistance in glioblastoma through ITGA5-PI3K/AKT axis
by: Ying Shi, et al.
Published: (2025-12-01)
by: Ying Shi, et al.
Published: (2025-12-01)
Expression Profiles of ITGA8 and VANGL2 Are Altered in Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
by: Nikola Pavlović, et al.
Published: (2024-07-01)
by: Nikola Pavlović, et al.
Published: (2024-07-01)
The silencing effect of miR-30a on ITGA4 gene expression in vitro: an approach for gene therapy
by: Leila Darzi, et al.
Published: (2017-01-01)
by: Leila Darzi, et al.
Published: (2017-01-01)
High expression ITGA2 affects the expression of MET, PD-L1, CD4 and CD8 with the immune microenvironment in pancreatic cancer patients
by: Liquan Jin, et al.
Published: (2023-10-01)
by: Liquan Jin, et al.
Published: (2023-10-01)
miR-4739/ITGA10/PI3K signaling regulates differentiation and apoptosis of osteoblast
by: Yibo Song, et al.
Published: (2022-12-01)
by: Yibo Song, et al.
Published: (2022-12-01)
Low expression of WWC1, a tumor suppressor gene, is associated with aggressive breast cancer and poor survival outcome
by: Zhanwei Wang, et al.
Published: (2019-07-01)
by: Zhanwei Wang, et al.
Published: (2019-07-01)
Macrophages Promote Ovarian Cancer-Mesothelial Cell Adhesion by Upregulation of ITGA2 and VEGFC in Mesothelial Cells
by: Seung-Kye Cho, et al.
Published: (2023-01-01)
by: Seung-Kye Cho, et al.
Published: (2023-01-01)
ITGA5 is associated with prognosis marker and immunosuppression in head and neck squamous cell carcinoma
by: Jianmin Liu, et al.
Published: (2024-10-01)
by: Jianmin Liu, et al.
Published: (2024-10-01)
Expression and prognostic analyses of ITGA11, ITGB4 and ITGB8 in human non-small cell lung cancer
by: Pancheng Wu, et al.
Published: (2019-12-01)
by: Pancheng Wu, et al.
Published: (2019-12-01)
Anlotinib inhibits c-MET and ITGA2 in the treatment of anaplastic thyroid carcinoma
by: Shunshun Zhao, et al.
Published: (2025-04-01)
by: Shunshun Zhao, et al.
Published: (2025-04-01)
Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression
by: Ling Ding, et al.
Published: (2025-08-01)
by: Ling Ding, et al.
Published: (2025-08-01)
circRNA ITGA7 restrains growth and enhances radiosensitivity by up-regulating SMAD4 in colorectal carcinoma
by: Li Wei, et al.
Published: (2023-01-01)
by: Li Wei, et al.
Published: (2023-01-01)
Identification and isolation of human testicular peritubular myoid cells and Leydig cells by a combination of ITGA9 and NGFR
by: Sha Han, et al.
Published: (2025-05-01)
by: Sha Han, et al.
Published: (2025-05-01)
Prognostic and clinicopathological significance of fatty acid synthase in breast cancer: A systematic review and meta-analysis
by: Binyan Liu, et al.
Published: (2023-04-01)
by: Binyan Liu, et al.
Published: (2023-04-01)
Prognostic significance of the logistic regression model for assessing the risk of recurrence in patients with prostate cancer after radical prostatectomy
by: S. A. Reva, et al.
Published: (2022-12-01)
by: S. A. Reva, et al.
Published: (2022-12-01)
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner
by: Chuanpeng Zhang, et al.
Published: (2024-02-01)
by: Chuanpeng Zhang, et al.
Published: (2024-02-01)
Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma [Retraction]
by: Fan J, et al.
Published: (2021-12-01)
by: Fan J, et al.
Published: (2021-12-01)
Oligomeric Proanthocyanidins Reverse Lenvatinib Resistance in Hepatocellular Carcinoma Through ITGA3-Mediated Pathway
by: Takayuki Noma, et al.
Published: (2025-09-01)
by: Takayuki Noma, et al.
Published: (2025-09-01)
METTL3 promotes the osteogenic differentiation of periosteum-derived MSCs via regulation of the HOXD8/ITGA5 axis in congenital pseudarthrosis
by: Weihua Ye, et al.
Published: (2024-06-01)
by: Weihua Ye, et al.
Published: (2024-06-01)
Clinicopathologic significance of heat shock protein 60 as a survival predictor in breast carcinoma
by: Qing Wang, et al.
Published: (2024-08-01)
by: Qing Wang, et al.
Published: (2024-08-01)
Knockdown of ITGA2 Promotes Pyroptosis in Thyroid Cancer by Regulating the DNA Damage Response
by: Liang Yan, et al.
Published: (2025-08-01)
by: Liang Yan, et al.
Published: (2025-08-01)
Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration
by: Muhammad Ashraf, et al.
Published: (2023-07-01)
by: Muhammad Ashraf, et al.
Published: (2023-07-01)
Mutations of the PIK3CA gene in patients with breast cancer in the Krasnoyarsk region
by: A. V. Zyuzyukina, et al.
Published: (2024-07-01)
by: A. V. Zyuzyukina, et al.
Published: (2024-07-01)
Clinical Significance of Tumor Grade in Triple-Negative Breast Cancer: A Retrospective Cohort Analysis
by: Neya Ramanan, et al.
Published: (2025-05-01)
by: Neya Ramanan, et al.
Published: (2025-05-01)
ITGA4 gene methylation status in chronic lymphocytic leukemia
by: Hanaa RM Attia, et al.
Published: (2020-08-01)
by: Hanaa RM Attia, et al.
Published: (2020-08-01)
ITGA3–MET interaction promotes papillary thyroid cancer progression via ERK and PI3K/AKT pathways
by: Youmian Lan, et al.
Published: (2025-12-01)
by: Youmian Lan, et al.
Published: (2025-12-01)
Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells
by: Yang Xiao, et al.
Published: (2024-11-01)
by: Yang Xiao, et al.
Published: (2024-11-01)
Similar Items
-
Immunological role and prognostic value of ITGA3 and ITGA5 in oral squamous cell carcinoma
by: Lujuan Wang, et al.
Published: (2025-08-01) -
MUC1 promotes cervical squamous cell carcinoma through ERK phosphorylation-mediated regulation of ITGA2/ITGA3
by: Aiqin Zhao, et al.
Published: (2024-05-01) -
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer
by: Wei Tan, et al.
Published: (2024-11-01) -
PSAT1 Promotes Metastasis via p-AKT/SP1/ITGA2 Axis in Estrogen Receptor-Negative Breast Cancer Cell
by: Xingda Zhang, et al.
Published: (2024-08-01) -
ITGA11, a Prognostic Factor Associated with Immunity in Gastric Adenocarcinoma
by: Yang X, et al.
Published: (2024-02-01)
