Proton therapy for head and neck cancer therapy: A real-world data case study from Bulgaria

Head and neck cancers (HNC) are one of the most severe types of cancer in Europe, accounting for almost 4.5% of all cancer types, according to GLOBOCAN. The incidence is geographically variable, with higher rates observed in Eastern and Southern Europe than in Northern and Western Europe. Proton and...

Full description

Bibliographic Details
Published in:	Pharmacia
Main Authors:	Maria Dimitrova, Nezabravka Tsvetanova, Daniel Penchev, Guenka Petrova
Format:	Article
Language:	English
Published:	Pensoft Publishers 2024-07-01
Online Access:	https://pharmacia.pensoft.net/article/129379/download/pdf/

Similar Items

A Real-World Study of Electronic Prescriptions and Medication Adherence in Bulgaria
by: Nikol Georgieva, et al.
Published: (2025-09-01)

Treatment patterns, adherence to international guidelines, and financial mechanisms of the market access of advanced breast cancer therapy in Bulgaria
by: Stephanie Karanyotova, et al.
Published: (2023-03-01)

Methodologies to Increase the Level of Evidence of Real-life Proton Therapy in Head and Neck Tumors
by: Francesco Dionisi, MD, et al.
Published: (2021-06-01)

Economic consequences of the implementation of primary DNA-HPV genotype testing in Bulgaria
by: Maria Dimitrova, et al.
Published: (2024-12-01)

Clinical Review of Proton Therapy in the Treatment of Unilateral Head and Neck Cancers
by: Robert H. Press, MD, et al.
Published: (2021-06-01)

Financial Toxicity in Head and Neck Cancer Patients Treated With Proton Therapy
by: Grace L. Smith, MD, PhD, MPH, et al.
Published: (2021-06-01)

Real-life study of the cost-effectiveness of benralizumab vs previous care in Bulgaria
by: Konstantin Tachkov, et al.
Published: (2025-07-01)

Proton Therapy Outcomes for Head and Neck Cutaneous Melanoma: Proton Collaborative Group Analysis
by: James E. Han, MD, et al.
Published: (2022-07-01)

Adjuvant Reirradiation With Proton Therapy in Head and Neck Squamous Cell Carcinoma
by: Kristin Hsieh, MD, et al.
Published: (2024-04-01)

Synthetic computed tomography techniques for adaptive proton therapy in head and neck cancers
by: Suryakant Kaushik, et al.
Published: (2025-10-01)

National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer
by: Johannes A. Langendijk, MD, PhD, et al.
Published: (2021-06-01)

Digital health in Bulgaria: Imagination or possible reality?
by: Maria Dimitrova, et al.
Published: (2023-08-01)

Adherence to Acromegaly Treatment and Analysis of the Related Factors—A Real-World Study in Bulgaria
by: Maria Kamusheva, et al.
Published: (2023-01-01)

Photon versus Proton Therapy in the Management of Head and Neck Cancer: A Systematic Review
by: S Sowmya, et al.
Published: (2025-11-01)

Using proton therapy to treat head and neck cancer and oral squamous cell carcinoma
by: Mohamed Imath, et al.
Published: (2024-06-01)

Proton Therapy for Head and Neck Cancer: A 12-Year, Single-Institution Experience
by: G. Brandon Gunn, MD, et al.
Published: (2021-06-01)

The effectiveness of neoadjuvant chemotherapy prior to proton beam therapy for head and neck tumors
by: Alexey V. Nezvetskiy, et al.
Published: (2025-01-01)

Study of head and neck squamous cell carcinoma transcriptome after proton therapy
by: E. D. Jumaniyazova, et al.
Published: (2024-04-01)

Economic burden of vulvar, vaginal, anal, penile and head &amp; neck cancers in Bulgaria
by: Hristina Lebanova, et al.
Published: (2024-10-01)

Pharmacotherapeutic Patterns and Patients’ Access to Pharmacotherapy for Some Rare Diseases in Bulgaria – A Pilot Comparative Study
by: Maria Kamusheva, et al.
Published: (2021-07-01)

CBCT-Based Adaptive Assessment Workflow for Intensity Modulated Proton Therapy for Head and Neck Cancer
by: De Ornelas Mariluz, PhD, et al.
Published: (2021-03-01)

Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base
by: Sarin Kitpanit, et al.
Published: (2020-04-01)

Pencil Beam Scanning Proton Therapy for Adolescents and Young Adults with Head and Neck Sarcomas
by: Miriam Vázquez, MD, et al.
Published: (2023-10-01)

Proton Beam Therapy for Head and Neck Carcinoma of Unknown Primary: Toxicity and Quality of Life
by: Alexander D. Sherry, BS, et al.
Published: (2021-06-01)

Cost-Effectiveness Models of Proton Therapy for Head and Neck: Evaluating Quality and Methods to Date
by: Danmeng Huang, PhD, et al.
Published: (2021-06-01)

A Real-World Study on Pulmonary Arterial Hypertension in Bulgaria: A Single-Center Retrospective Study From 2012 to 2022
by: Vasil Velchev, et al.
Published: (2025-01-01)

Analysis Of Patients' Opinion Of Prescribed Medicines: A Questionnaire - Based Pilot Study In Bulgaria
by: Zornitsa Emilova Mitkova, et al.
Published: (2023-11-01)

Comparison of single and dual energy CT for stopping power determination in proton therapy of head and neck cancer
by: Vicki Trier Taasti, et al.
Published: (2018-04-01)

Benefit of range uncertainty reduction in robust optimisation for proton therapy of brain, head-and-neck and breast cancer patients
by: Ivanka Sojat Tarp, et al.
Published: (2024-07-01)

The Biological Basis for Enhanced Effects of Proton Radiation Therapy Relative to Photon Radiation Therapy for Head and Neck Squamous Cell Carcinoma
by: Li Wang, MD, PhD, et al.
Published: (2021-06-01)

Independent validation of a dysphagia dose response model for the selection of head and neck cancer patients to proton therapy
by: Petros Kalendralis, et al.
Published: (2022-10-01)

Enhanced radiosensitivity of head and neck cancer cells to proton therapy via hyperthermia-induced homologous recombination deficiency
by: Tim Heemskerk, et al.
Published: (2025-03-01)

Dosimetric benefits of customised mouth-bite for head neck cancer patients undergoing modern proton therapy – An audit
by: Sapna Nangia, et al.
Published: (2024-09-01)

Acute toxicities in proton therapy for head and neck cancer – A matched analysis of the DAHANCA 35 feasibility study
by: K. Nowicka-Matus, et al.
Published: (2024-09-01)

Large anatomical changes in head-and-neck cancers – A dosimetric comparison of online and offline adaptive proton therapy
by: Mislav Bobić, et al.
Published: (2023-05-01)

Robust Intensity Modulated Proton Therapy (IMPT) Increases Estimated Clinical Benefit in Head and Neck Cancer Patients.
by: Lisanne V van Dijk, et al.
Published: (2016-01-01)

Quantifying the Dosimetric Impact of Proton Range Uncertainties on RBE-Weighted Dose Distributions in Intensity-Modulated Proton Therapy for Bilateral Head and Neck Cancer
by: Suresh Rana, et al.
Published: (2024-06-01)

Proton beam therapy in repeat irradiation of recurrent head and neck tumors: analysis of short-term results
by: D. I. Smyk, et al.
Published: (2023-03-01)

Long-term nutrition therapy leads to survival benefit in head and neck cancer patients receiving targeted or immunotherapy. A retrospective cohort study with real-world data
by: Barbara Belak, et al.
Published: (2025-11-01)

Short-course pembrolizumab and continuous afatinib therapy for recurrent or metastatic head and neck squamous cell carcinoma: a real-world data analysis
by: Hsiang-Fong Kao, et al.
Published: (2022-11-01)