Study on radiosensitization performance of dual-energy X-ray intraoperative radiotherapy based on Monte Carlo simulations

Radiosensitization with nanoparticles (NPs) remains a feasible way to enhance the efficiency of intraoperative radiotherapy (IORT). For the first time, this study proposed the energy-selective method with application of NPs for IORT, of which a magnetic modulated two-target X-ray tube was employed....

Full description

Bibliographic Details
Published in:	Nuclear Engineering and Technology
Main Authors:	Limin Jin, Chang Liu, Li Chen, Xi Zhang, Wenmin Han, Qiliang Peng
Format:	Article
Language:	English
Published:	Elsevier 2026-07-01
Subjects:	Intraoperative radiotherapy Radiosensitization nanoparticle Dose enhancement Two-target X-ray tube Monte Carlo simulation
Online Access:	http://www.sciencedirect.com/science/article/pii/S1738573326001919

Similar Items

Design of a magnetic-modulated target-selective X-ray tube to improve the energy distribution for intraoperative radiotherapy
by: Limin Jin, et al.
Published: (2025-07-01)

Monte Carlo simulations in radiotherapy dosimetry
by: Pedro Andreo
Published: (2018-06-01)

Recent progress in Monte Carlo simulation on gold nanoparticle radiosensitization
by: James C. L. Chow
Published: (2018-10-01)

A review on lymphocyte radiosensitivity and its impact on radiotherapy
by: Harald Paganetti, et al.
Published: (2023-08-01)

Investigation and Comparison of Metal Nanoparticles on Dose Enhancement Effect in Radiotherapy Using Monte Carlo Simulation Method
by: Mohammad Reza Madi, et al.
Published: (2022-04-01)

Evaluating deposited radiation energy amount and collision quantities of small-molecule radiosensitizers through Monte Carlo simulations
by: Ghada ALMisned, et al.
Published: (2024-07-01)

Do cell culturing influence the radiosensitizing effect of gold nanoparticles: a Monte Carlo study
by: J. Antunes, et al.
Published: (2025-04-01)

Comparison of treatment plans calculated by Ray Tracing and Monte Carlo algorithms for head and thorax radiotherapy with Cyberknife
by: Galonske Kirsten, et al.
Published: (2017-09-01)

DNA Dosimetry with Gold Nanoparticle Irradiated by Proton Beams: A Monte Carlo Study on Dose Enhancement
by: Ngoc Han Huynh, et al.
Published: (2021-11-01)

Radiosensitization by Gold Nanoparticles: Impact of the Size, Dose Rate, and Photon Energy
by: Kirill V. Morozov, et al.
Published: (2020-05-01)

Improving the efficacy of combined radiotherapy and immunotherapy: focusing on the effects of radiosensitivity
by: Zhiru Gao, et al.
Published: (2023-05-01)

DNA Damage of Iron-Gold Nanoparticle Heterojunction Irradiated by kV Photon Beams: A Monte Carlo Study
by: James C. L. Chow, et al.
Published: (2023-08-01)

Capture γ-Ray Dose Equivalent at Double-Bend Maze Entrance: Monte Carlo Simulation and Analytical Methods and Measurements
by: Reza Eghdam-Zamiri, et al.
Published: (2022-08-01)

Exploring the impact of anode material on X-ray photon fluence and characteristics: A Monte Carlo simulation study
by: Hassan Ouhadda, et al.
Published: (2024-06-01)

Dosimetry effects caused by unilateral and bilateral hip prostheses: A monte carlo case study in megavoltage photon radiotherapy for computed tomography data without metal artifacts
by: Courage Mahuvava, et al.
Published: (2018-01-01)

Evaluation of Dosimetric Effect of Bone Scatter on Nanoparticle-Enhanced Orthovoltage Radiotherapy: A Monte Carlo Phantom Study
by: Afia Sadiq, et al.
Published: (2022-08-01)

Depth Dose Enhancement in Orthovoltage Nanoparticle-Enhanced Radiotherapy: A Monte Carlo Phantom Study
by: James C. L. Chow, et al.
Published: (2023-06-01)

Estimation of Dose Perturbation Due to the Presence of Metal Hip Prostheses in Radiotherapy with Electron and Photon Beams: A Monte Carlo Study
by: Morteza Hashemizadeh, et al.
Published: (2024-07-01)

A Novel Treatment Planning Design for Intraoperative Electron Radiation Therapy (IOERT) using an Electronic Board
by: Zahra Pouyanrad, et al.
Published: (2024-04-01)

Estimating Specific Patient Organ Dose for Chest CT Examinations with Monte Carlo Method
by: Yang Yang, et al.
Published: (2021-09-01)

Dosimetric analysis of Rhizophora-based phantom material in radiation therapy applications using Monte Carlo GATE simulation
by: Siti Hajar Zuber, et al.
Published: (2023-01-01)

Shielding disc backscatter calculations in intraoperative radiotherapy using a Monte Carlo simulation based on the method of energy spectra reconstruction
by: Adam Ryczkowski, et al.
Published: (2025-04-01)

Dosimetric assessment and secondary cancer risk in breast radiotherapy: a Monte Carlo approach
by: Mirko Salomón Alva-Sánchez, et al.
Published: (2022-09-01)

Calculation of Dose Perturbation in Radiotherapy of Head and Neck Tumors Due to the Presence of Dental Implants: A Monte Carlo Study
by: Morteza Hashemizadeh, et al.
Published: (2024-07-01)

Application of Monte Carlo Method for Gamma ray Attenuation Properties of Lead Zinc Borate Glasses
by: Urkiye Akar Tarım, et al.
Published: (2018-12-01)

Biological modeling of gadolinium-based nanoparticles radio-enhancement for kilovoltage photons: a Monte Carlo study
by: Jianan Wu, et al.
Published: (2023-05-01)

Monte Carlo-based software for 3D personalized dose calculations in image-guided radiotherapy
by: Coralie Le Deroff, et al.
Published: (2022-01-01)

Iodinated Copper–Cysteamine Nanoparticles as Radiosensitizers for Tumor Radiotherapy
by: Miaomiao Zhang, et al.
Published: (2025-01-01)

Simulation of industrial 60Со gamma-ray source by Monte-Carlo method
by: V. I. Gulik
Published: (2018-09-01)

Evaluation of Lung Dose in Esophageal Cancer Radiotherapy Using Monte Carlo Simulation
by: Tayyeb Pourfallah, et al.
Published: (2020-02-01)

Quercetin as a radiosensitizer for enhanced efficacy of radiotherapy in MCF-7 breast cancer cells
by: Mohammad Banparvar, et al.
Published: (2024-12-01)

Synchrotron X-ray Irradiation of a Rat’s Head Model: Monte Carlo Study of Chromatic Gel Dosimetry
by: Yarden Peleg Walg, et al.
Published: (2021-08-01)

Monte Carlo simulation and optimization of neutron ray shielding performance of related materials
by: Tongyan Cui, et al.
Published: (2024-09-01)

Study of γ-ray energy losses in the ionic crystalsusingMonte Carlo code
by: Abdulhadi M. Ghelab, et al.
Published: (2015-09-01)

Monte Carlo simulation of a novel medical linac concept for highly conformal x-ray FLASH cancer radiotherapy
by: Deae-eddine Krim, et al.
Published: (2025-05-01)

Monte Carlo modeling of multileaf collimators using the code Geant4
by: Alex Cristóvão Holanda de Oliveira, et al.
Published: (2015-05-01)

Gelsolin knockdown confers radiosensitivity to glioblastoma cells
by: Dezhi Gao, et al.
Published: (2024-05-01)

Experimental verification of a methodology for Monte Carlo modeling of multileaf collimators using the code Geant4
by: Alex Cristóvão Holanda de Oliveira, et al.
Published: (2018-05-01)

Monte Carlo Simulations in Nanomedicine: Advancing Cancer Imaging and Therapy
by: James C. L. Chow
Published: (2025-01-01)

Dose Enhancement for the Flattening-Filter-Free and Flattening-Filter Photon Beams in Nanoparticle-Enhanced Radiotherapy: A Monte Carlo Phantom Study
by: Stefano Martelli, et al.
Published: (2020-03-01)