Endoplasmic reticulum stress: a novel targeted approach to repair bone defects by regulating osteogenesis and angiogenesis

Abstract Bone regeneration therapy is clinically important, and targeted regulation of endoplasmic reticulum (ER) stress is important in regenerative medicine. The processing of proteins in the ER controls cell fate. The accumulation of misfolded and unfolded proteins occurs in pathological states,...

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Bibliographic Details
Published in:	Journal of Translational Medicine
Main Authors:	Tingyu Wu, Yaping Jiang, Weipeng Shi, Yingzhen Wang, Tao Li
Format:	Article
Language:	English
Published:	BMC 2023-07-01
Subjects:	Endoplasmic reticulum stress Unfolded protein response Osteogenesis Angiogenesis High glucose Inflammation
Online Access:	https://doi.org/10.1186/s12967-023-04328-8

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