Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.
<h4>Background</h4>Neural conversion from human embryonic stem cells (hESCs) has been demonstrated in a variety of systems including chemically defined suspension culture, not requiring extrinsic signals, as well as in an adherent culture method that involves dual SMAD inhibition using N...
| 發表在: | PLoS ONE |
|---|---|
| Main Authors: | Rickie Patani, Alastair Compston, Clare A Puddifoot, David J A Wyllie, Giles E Hardingham, Nicholas D Allen, Siddharthan Chandran |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Public Library of Science (PLoS)
2009-10-01
|
| 在線閱讀: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0007327&type=printable |
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