Emerging Roles of the Unique Molecular Chaperone Cosmc in the Regulation of Health and Disease
The core-1 β1-3galactosyltransferase-specific chaperone 1 (Cosmc) is a unique molecular chaperone of core-1 β1-3galactosyltransferase(C1GALT1), which typically functions inside the endoplasmic reticulum (ER). Cosmc helps C1GALT1 to fold correctly and maintain activity. It also participates in the sy...
| 出版年: | Biomolecules |
|---|---|
| 主要な著者: | Ting Xiang, Muchuan Qiao, Jiangbo Xie, Zheng Li, Hailong Xie |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
MDPI AG
2022-11-01
|
| 主題: | |
| オンライン・アクセス: | https://www.mdpi.com/2218-273X/12/12/1732 |
類似資料
Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens
著者:: Xu F, 等
出版事項: (2020-02-01)
著者:: Xu F, 等
出版事項: (2020-02-01)
Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens [Retraction]
著者:: Xu F, 等
出版事項: (2022-11-01)
著者:: Xu F, 等
出版事項: (2022-11-01)
Overexpression of Tn antigen induces chronic pancreatitis in mice
著者:: Baris Mercanoglu, 等
出版事項: (2025-04-01)
著者:: Baris Mercanoglu, 等
出版事項: (2025-04-01)
COSMC-Regulated O-Glycosylation: A Bioinformatics-Driven Biomarker Identification for Stratifying Glioblastoma Stem Cell Subtypes
著者:: Sara Sadat Aghamiri, 等
出版事項: (2024-12-01)
著者:: Sara Sadat Aghamiri, 等
出版事項: (2024-12-01)
Cosmc Disruption-Mediated Aberrant O-glycosylation Suppresses Breast Cancer Cell Growth via Impairment of CD44
著者:: Du T, 等
出版事項: (2020-01-01)
著者:: Du T, 等
出版事項: (2020-01-01)
Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn+ colorectal cancer cells from modifying their O-glycosylation status
著者:: Wen Hu, 等
出版事項: (2023-05-01)
著者:: Wen Hu, 等
出版事項: (2023-05-01)
Immature O-glycans recognized by the macrophage glycoreceptor CLEC10A (MGL) are induced by 4-hydroxy-tamoxifen, oxidative stress and DNA-damage in breast cancer cells
著者:: Anna-Katharina Kurze, 等
出版事項: (2019-08-01)
著者:: Anna-Katharina Kurze, 等
出版事項: (2019-08-01)
O-GlcNAcylation determines the function of the key O-GalNAc glycosyltransferase C1GalT1 in bladder cancer
著者:: Jiang Yazhuo, 等
出版事項: (2024-08-01)
著者:: Jiang Yazhuo, 等
出版事項: (2024-08-01)
Unraveling the role of C1GALT1 in abnormal glycosylation and colorectal cancer progression
著者:: Hong Tian, 等
出版事項: (2024-04-01)
著者:: Hong Tian, 等
出版事項: (2024-04-01)
A diverse interactome of the molecular chaperone CCT/TRiC monomers
著者:: Carmen M. Córdoba-Beldad, 等
出版事項: (2025-09-01)
著者:: Carmen M. Córdoba-Beldad, 等
出版事項: (2025-09-01)
Bioinformatic Analysis of C1GALT1 in Cancer: Insights Into Prognosis, Metastasis and Therapeutic Potential
著者:: Ecem Kalemoglu, 等
出版事項: (2025-06-01)
著者:: Ecem Kalemoglu, 等
出版事項: (2025-06-01)
Fluorinated Galactoses Inhibit Galactose-1-Phosphate Uridyltransferase and Metabolically Induce Galactosemia-like Phenotypes in HEK-293 Cells
著者:: Verena Janes, 等
出版事項: (2020-03-01)
著者:: Verena Janes, 等
出版事項: (2020-03-01)
Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment
著者:: Patricia Guerrero-Ochoa, 等
出版事項: (2022-05-01)
著者:: Patricia Guerrero-Ochoa, 等
出版事項: (2022-05-01)
GroEL—A Versatile Chaperone for Engineering and a Plethora of Applications
著者:: Maria S. Yurkova, 等
出版事項: (2022-04-01)
著者:: Maria S. Yurkova, 等
出版事項: (2022-04-01)
The Function of Different Subunits of the Molecular Chaperone CCT in the Microsporidium <i>Nosema bombycis</i>: NbCCTζ Interacts with NbCCTα
著者:: Sheng Xu, 等
出版事項: (2024-03-01)
著者:: Sheng Xu, 等
出版事項: (2024-03-01)
The (Sialyl) Tn antigen: Contributions to immunosuppression in gastrointestinal cancers
著者:: Christabelle Rajesh, 等
出版事項: (2023-01-01)
著者:: Christabelle Rajesh, 等
出版事項: (2023-01-01)
Editorial: A focus on chaperone clients
著者:: Amnon Horovitz, 等
出版事項: (2023-03-01)
著者:: Amnon Horovitz, 等
出版事項: (2023-03-01)
The CCTδ subunit of the molecular chaperone CCT is required for correct localisation of p150Glued to spindle poles during mitosis
著者:: Carmen M. Córdoba-Beldad, 等
出版事項: (2024-09-01)
著者:: Carmen M. Córdoba-Beldad, 等
出版事項: (2024-09-01)
Sialyl-Tn glycan epitope as a target for pancreatic cancer therapies
著者:: Rafaela Abrantes, 等
出版事項: (2024-09-01)
著者:: Rafaela Abrantes, 等
出版事項: (2024-09-01)
Clinical impacts of Artocarpus lakoocha agglutinin-binding glycans for prognosis and treatment of cholangiocarcinoma
著者:: Phisit Sintusen, 等
出版事項: (2025-01-01)
著者:: Phisit Sintusen, 等
出版事項: (2025-01-01)
Cytosolic UDP-Gal biosynthetic machinery is required for dimerization of SLC35A2 in the Golgi membrane and its interaction with B4GalT1
著者:: Wojciech Wiertelak, 等
出版事項: (2025-03-01)
著者:: Wojciech Wiertelak, 等
出版事項: (2025-03-01)
A novel mechanism for C1GALT1 in the regulation of gastric cancer progression
著者:: Xiaoxia Dong, 等
出版事項: (2021-08-01)
著者:: Xiaoxia Dong, 等
出版事項: (2021-08-01)
Immunohistochemical analysis of Tn antigen expression in colorectal adenocarcinoma and precursor lesions
著者:: Gabrielle E. Dombek, 等
出版事項: (2022-12-01)
著者:: Gabrielle E. Dombek, 等
出版事項: (2022-12-01)
M CELLS ARE THE IMPORTANT POST IN THE INITIATION OF IMMUNE RESPONSE IN INTESTINE
著者:: A. S. Bykov, 等
出版事項: (2018-11-01)
著者:: A. S. Bykov, 等
出版事項: (2018-11-01)
Single-Ring Intermediates Are Essential for Some Chaperonins
著者:: Jay M. Bhatt, 等
出版事項: (2018-04-01)
著者:: Jay M. Bhatt, 等
出版事項: (2018-04-01)
Antiretroviral Therapy Dampens Mucosal CD4<sup>+</sup> T Lamina Propria Lymphocytes Immune Activation in Long-Term Treated People Living with HIV-1
著者:: Alessandro Lazzaro, 等
出版事項: (2021-07-01)
著者:: Alessandro Lazzaro, 等
出版事項: (2021-07-01)
Abstract OR-11: Conformations of a Viral Chaperonin in Different Nucleotide-Bound States
著者:: Tatiana B. Stanishneva-Konovalova, 等
出版事項: (2019-06-01)
著者:: Tatiana B. Stanishneva-Konovalova, 等
出版事項: (2019-06-01)
Chaperonins: Nanocarriers with Biotechnological Applications
著者:: Sergio Pipaón, 等
出版事項: (2021-02-01)
著者:: Sergio Pipaón, 等
出版事項: (2021-02-01)
Long Non-Coding RNA B3GALT5-AS1 Suppresses Keloid Progression by Regulating the β-Trcp1-Mediated Ubiquitination of HuR
著者:: Ye W, 等
出版事項: (2024-04-01)
著者:: Ye W, 等
出版事項: (2024-04-01)
Down-Regulation of C1GALT1 Enhances the Progression of Cholangiocarcinoma through Activation of AKT/ERK Signaling Pathways
著者:: Juthamas Khiaowichit, 等
出版事項: (2022-01-01)
著者:: Juthamas Khiaowichit, 等
出版事項: (2022-01-01)
Beyond the Mohawk Warrior: Reinterpreting Benjamin West’s Evocations of American Indians
著者:: Julia Sienkewicz
出版事項: (2009-11-01)
著者:: Julia Sienkewicz
出版事項: (2009-11-01)
The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to the base of primary cilia
著者:: Joshua Linnert, 等
出版事項: (2025-03-01)
著者:: Joshua Linnert, 等
出版事項: (2025-03-01)
Galactokinase 1 is the source of elevated galactose‐1‐phosphate and cerebrosides are modestly reduced in a mouse model of classic galactosemia
著者:: Linley Mangini, 等
出版事項: (2024-07-01)
著者:: Linley Mangini, 等
出版事項: (2024-07-01)
Local Flexibility of a New Single-Ring Chaperonin Encoded by Bacteriophage AR9 <i>Bacillus subtilis</i>
著者:: Olga S. Sokolova, 等
出版事項: (2022-09-01)
著者:: Olga S. Sokolova, 等
出版事項: (2022-09-01)
CaptureSeq: Hybridization-Based Enrichment of <i>cpn60</i> Gene Fragments Reveals the Community Structures of Synthetic and Natural Microbial Ecosystems
著者:: Matthew G. Links, 等
出版事項: (2021-04-01)
著者:: Matthew G. Links, 等
出版事項: (2021-04-01)
The Possible Role of the Type I Chaperonins in Human Insulin Self-Association
著者:: Federica Pizzo, 等
出版事項: (2022-03-01)
著者:: Federica Pizzo, 等
出版事項: (2022-03-01)
Prl and B4GALT-1 gene polymorphism and their association with milk production traits in crossbred cattle of Kerala
著者:: TINA SADAN, 等
出版事項: (2021-04-01)
著者:: TINA SADAN, 等
出版事項: (2021-04-01)
Convergent synthesis of the tetrasaccharide repeating unit of the cell wall lipopolysaccharide of Escherichia coli O40
著者:: Abhijit Sau, 等
出版事項: (2012-11-01)
著者:: Abhijit Sau, 等
出版事項: (2012-11-01)
Genetic characterisation of antibiotic resistance transposons Tn6608 and Tn6609 isolated from clinical Pseudomonas strains in Cyprus
著者:: Vaheesan Rajabal, 等
出版事項: (2021-09-01)
著者:: Vaheesan Rajabal, 等
出版事項: (2021-09-01)
Analysis of common mutation for GALT gene in newborns with galacatosemia Nineveh governorate
著者:: Owayes M Alhassani, 等
出版事項: (2014-01-01)
著者:: Owayes M Alhassani, 等
出版事項: (2014-01-01)
類似資料
-
Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens
著者:: Xu F, 等
出版事項: (2020-02-01) -
Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens [Retraction]
著者:: Xu F, 等
出版事項: (2022-11-01) -
Overexpression of Tn antigen induces chronic pancreatitis in mice
著者:: Baris Mercanoglu, 等
出版事項: (2025-04-01) -
COSMC-Regulated O-Glycosylation: A Bioinformatics-Driven Biomarker Identification for Stratifying Glioblastoma Stem Cell Subtypes
著者:: Sara Sadat Aghamiri, 等
出版事項: (2024-12-01) -
Cosmc Disruption-Mediated Aberrant O-glycosylation Suppresses Breast Cancer Cell Growth via Impairment of CD44
著者:: Du T, 等
出版事項: (2020-01-01)
