Enhanced calcium release in the acute neuronopathic form of Gaucher disease

Gaucher disease is an inherited metabolic disorder caused by defective activity of the lysosomal enzyme, glucocerebrosidase, resulting in accumulation of the lipids, glucosylceramide (GlcCer), and glucosylsphingosine (GlcSph). Little is known about the mechanism leading from lipid accumulation to di...

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Bibliographic Details
Published in:	Neurobiology of Disease
Main Authors:	Dori Pelled, Selena Trajkovic-Bodennec, Emyr Lloyd-Evans, Ellen Sidransky, Raphael Schiffmann, Anthony H. Futerman
Format:	Article
Language:	English
Published:	Elsevier 2005-02-01
Subjects:	Gaucher disease Lysosomal storage disease Glucocerebrosidase Glucosylceramide Glucosylsphingosine Calcium
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996104002219

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