Bacterial Mixology: Combining Pharmacodynamic Models to Predict In Vitro Competition of MCR-1-Harboring <i>E. coli</i>

The emergence of mobile colistin resistance (<i>mcr</i>)-mediated polymyxin resistance has resulted in a significant detriment to the utility of the polymyxins in the clinical setting. Though the risk for horizontal transfer of an <i>mcr</i>-containing plasmid is a major comp...

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Bibliographic Details

Published in:	Antibiotics
Main Authors:	Nicholas M. Smith, Arthur Chan, Thomas D. Nguyen, Jacob T. Dumbleton
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	<i>mcr</i> antimicrobial resistance Gram-negative bacteria polymyxin resistance <i>Escherichia coli</i>
Online Access:	https://www.mdpi.com/2079-6382/11/1/34