ZNF3 regulates proliferation, migration and invasion through MMP1 and TWIST in colorectal cancer

Colorectal cancer (CRC) is a malignant tumor with a high incidence and mortality worldwide. Currently, the underlying molecular mechanisms of CRC are still unclear. Zinc finger protein 3 (ZNF3) is a zinc-finger transcription factor that has been reported as a candidate for breast cancer prognosis, s...

Full description

Bibliographic Details
Published in:	Acta Biochimica et Biophysica Sinica
Main Authors:	Du Le, Liu Ning, Jin Jianfeng, Cao Meng, Sun Yuantian, Gao Xinzheng, Ruan Banzhan, Yang Shangfeng, Ge Dongsheng, Ye Yingzhuan, Zhou Yinxi, Chen Erfei, Yang Jin
Format:	Article
Language:	English
Published:	China Science Publishing & Media Ltd. 2022-12-01
Subjects:	ZNF3 colorectal cancer proliferation migration invasion
Online Access:	https://www.sciengine.com/doi/10.3724/abbs.2022187

Similar Items

ZNF692 promotes cell proliferation, invasion and migration of human prostate cancer cells by targeting the EMT signaling pathway
by: Hanmin Chen, et al.
Published: (2024-01-01)

ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway
by: Di Zheng, et al.
Published: (2024-04-01)

ZNF259 inhibits non-small cell lung cancer cells proliferation and invasion by FAK-AKT signaling
by: Shan Y, et al.
Published: (2017-12-01)

MicroRNA-339 inhibits human hepatocellular carcinoma proliferation and invasion via targeting ZNF689
by: Zeng H, et al.
Published: (2019-01-01)

ZNF521/EBF1 axis regulates AKR1B1 to promote the proliferation, migration, and invasion of gastric cancer cells
by: Yu Cheng, et al.
Published: (2023-03-01)

ZNF32 histidine 179 and 183 single-site and double-site mutations promote nuclear speckle formation but differentially regulate the proliferation of breast cancer cells
by: Chaosong Zhong, et al.
Published: (2025-02-01)

DUF3669, a “domain of unknown function” within ZNF746 and ZNF777, oligomerizes and contributes to transcriptional repression
by: Mohannad Al Chiblak, et al.
Published: (2019-12-01)

ZNF263 promotes gastric cancer cell growth by regulating TXNDC9 transcription
by: Silu Chen, et al.
Published: (2025-08-01)

SUZ12 knockdown restrains the proliferation, migration, and invasion of oral tongue squamous cell carcinoma through inhibiting DNMT1-mediated ZNF582 promoter methylation
by: Xiangwei Kong, et al.
Published: (2025-09-01)

Chicken CircZNF609 encodes a protein induced by IRES-like region that inhibits the proliferation and promotes the differentiation of myoblasts
by: Lei Li, et al.
Published: (2025-08-01)

Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma
by: Wenxia Meng, et al.
Published: (2019-01-01)

Genetic variants of ZNF746 and the level of plasma Parkin, PINK1, and ZNF746 proteins in patients with Parkinson's disease
by: Jolanta Dorszewska, et al.
Published: (2025-06-01)

Noxa inhibits oncogenesis through ZNF519 in gastric cancer and is suppressed by hsa-miR-200b-3p
by: Jin Shi, et al.
Published: (2024-03-01)

IL-8-mediated overexpression of ZNF274 promotes the proliferation and migration of colorectal cancer cells through the transactivation of MRPL40
by: Feng Du, et al.
Published: (2023-08-01)

THE1B may have no role in human pregnancy due to ZNF430-mediated silencing
by: Zheng Zuo
Published: (2023-05-01)

Zinc Finger Proteins in Head and Neck Squamous Cell Carcinomas: ZNF540 May Serve as a Biomarker
by: Joanna Sobocińska, et al.
Published: (2022-12-01)

Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest
by: Jian Zhang, et al.
Published: (2017-10-01)

ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells
by: Alejandra Sanchez-Briñas, et al.
Published: (2023-05-01)

ZNF280A promotes malignant melanoma development through regulating cell proliferation, apoptosis, and cell cycle
by: Wenjun Zheng, et al.
Published: (2025-04-01)

The Novel Zinc Finger Protein 587B Gene, ZNF587B, Regulates Cell Proliferation and Metastasis in Ovarian Cancer Cells in vivo and in vitro
by: Liu Y, et al.
Published: (2020-06-01)

ZNF143 in Chromatin Looping and Gene Regulation
by: Bingyu Ye, et al.
Published: (2020-04-01)

ZNF382 inhibits hepatocellular carcinoma (HCC) cell proliferation and motility and induces apoptosis by up-regulating SOX11
by: Zhi Liu, et al.
Published: (2021-04-01)

Insights into the pleiotropic roles of ZNF703 in cancer
by: Shuang Wang, et al.
Published: (2023-09-01)

ZNF580 – a brake on Interleukin-6
by: Philipp Stenzel, et al.
Published: (2018-10-01)

ZNF121 interacts with ZBRK1 and BRCA1 to regulate their target genes in mammary epithelial cells
by: Ang Luo, et al.
Published: (2018-12-01)

Variants in the ZNF469 gene in families with Brittle cornea syndrome and keratoconus
by: Qinghong Lin, et al.
Published: (2024-03-01)

The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
by: Zane A Gibbs, et al.
Published: (2020-06-01)

ZNF213 Facilitates ER Alpha Signaling in Breast Cancer Cells
by: Huijie Yang, et al.
Published: (2021-03-01)

Expression of ZNF281 in colorectal cancer correlates with response to radiotherapy and survival
by: Changjiang Qin, et al.
Published: (2023-12-01)

Identification of ZNF26 as a Prognostic Biomarker in Colorectal Cancer by an Integrated Bioinformatic Analysis
by: Jiaxin Liu, et al.
Published: (2021-06-01)

ZNF582 promoter methylation predicts cervical cancer radiosensitivity and ZNF582 protein overexpression reduces radiosensitivity by cell cycle arrest in S phase
by: Nayiyuan Wu, et al.
Published: (2022-12-01)

Targeted disruption of the mouse testis-enriched gene Znf230 does not affect spermatogenesis or fertility
by: Yunqiang Liu, et al.
Published: (2014-12-01)

Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis
by: Hong Peng, et al.
Published: (2024-04-01)

The zinc finger protein560(ZNF560) functions as a novel oncogenic gene in osteosarcoma
by: Xiong Dong, et al.
Published: (2025-01-01)

Multidimensional analysis suggests that ZNF433 is a promising biomarker for the diagnosis and prognosis of human cancers
by: Lingyu Xie, et al.
Published: (2025-06-01)

ZNF521 promotes acute myeloid leukemogenesis by suppressing the expression and acetylation of SMC3
by: Rong Qin, et al.
Published: (2024-09-01)

ZNF205 positively regulates RLR antiviral signaling by targeting RIG-I
by: Zhong Ni, et al.
Published: (2023-08-01)

RETRACTED: ZNF655 Promotes the Progression of Glioma Through Transcriptional Regulation of AURKA
by: Xu Chen, et al.
Published: (2022-02-01)

The Expression of ZNF268 and Its Role in The Cisplatin-based Chemoresistance of Breast Cancer
by: Weilu Wu, et al.
Published: (2023-08-01)

Esculin inhibits the proliferation of human nasopharyngeal carcinoma cell line HNE-3
by: SHEN Yong-hua, WANG Jun-feng, CHENG Ze-xing, FENG Juan-juan
Published: (2022-08-01)