Vaccine Candidate Double Mutant Variants of Enterotoxigenic <i>Escherichia coli</i> Heat-Stable Toxin
Heat-stable enterotoxin (ST) producing enterotoxigenic <i>Escherichia coli</i> (ETEC) strains are among the top four enteropathogens associated with moderate-to-severe diarrhea in children under five years in low-to-middle income countries, thus making ST a target for an ETEC vaccine. Ho...
| Published in: | Vaccines |
|---|---|
| Main Authors: | Ephrem Debebe Zegeye, Yuleima Diaz, Pål Puntervoll |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-02-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/10/2/241 |
Similar Items
Development of an enterotoxigenic Escherichia coli vaccine based on the heat-stable toxin
by: Ephrem Debebe Zegeye, et al.
Published: (2019-06-01)
by: Ephrem Debebe Zegeye, et al.
Published: (2019-06-01)
Impact of the <i>Escherichia coli</i> Heat-Stable Enterotoxin b (STb) on Gut Health and Function
by: Shahnawaz Butt, et al.
Published: (2020-12-01)
by: Shahnawaz Butt, et al.
Published: (2020-12-01)
Enterotoxigenic <i>Escherichia coli</i> Heat-Stable Toxin and Ebola Virus Delta Peptide: Similarities and Differences
by: Lilia I. Melnik, et al.
Published: (2022-01-01)
by: Lilia I. Melnik, et al.
Published: (2022-01-01)
Co-administered Tag-Less Toxoid Fusion 3xSTaN12S-mnLTR192G/L211A and CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) Induce Neutralizing Antibodies to 7 Adhesins (CFA/I, CS1-CS6) and Both Enterotoxins (LT, STa) of Enterotoxigenic Escherichia coli (ETEC)
by: Qiangde Duan, et al.
Published: (2018-06-01)
by: Qiangde Duan, et al.
Published: (2018-06-01)
Designing Vaccines to Neutralize Effective Toxin Delivery by Enterotoxigenic Escherichia coli
by: James M. Fleckenstein, et al.
Published: (2014-06-01)
by: James M. Fleckenstein, et al.
Published: (2014-06-01)
Modified Heat-Stable Toxins (hSTa) of Enterotoxigenic Escherichia coli Lose Toxicity but Display Antigenicity after Being Genetically Fused to Heat-Labile Toxoid LT(R192G)
by: Weiping Zhang, et al.
Published: (2011-09-01)
by: Weiping Zhang, et al.
Published: (2011-09-01)
Strong Association between Diarrhea and Concentration of Enterotoxigenic <i>Escherichia coli</i> Strain TW10722 in Stools of Experimentally Infected Volunteers
by: Oda Barth Vedøy, et al.
Published: (2023-02-01)
by: Oda Barth Vedøy, et al.
Published: (2023-02-01)
Heat-Labile Enterotoxin Decreases Macrophage Phagocytosis of Enterotoxigenic <i>Escherichia coli</i>
by: Ian E. Hollifield, et al.
Published: (2023-08-01)
by: Ian E. Hollifield, et al.
Published: (2023-08-01)
Isolation and evaluation of the pathogenicity of a hybrid shiga toxin-producing and Enterotoxigenic Escherichia coli in pigs
by: Danaya Nammuang, et al.
Published: (2024-10-01)
by: Danaya Nammuang, et al.
Published: (2024-10-01)
Targeting Enterotoxins: Advancing Vaccine Development for Enterotoxigenic <i>Escherichia coli</i> ETEC
by: Josune Salvador-Erro, et al.
Published: (2025-02-01)
by: Josune Salvador-Erro, et al.
Published: (2025-02-01)
Detection of heat-labile toxin in enterotoxigenic Escherichia coli using PCR-ELISA technique
by: Esfandiari P, et al.
Published: (2015-09-01)
by: Esfandiari P, et al.
Published: (2015-09-01)
Enterotoxigenic Escherichia coli - an overview
by: Beatriz Ernestina Cabilio Guth
Published: (2000-01-01)
by: Beatriz Ernestina Cabilio Guth
Published: (2000-01-01)
A Polyvalent Adhesin–Toxoid Multiepitope-Fusion-Antigen-Induced Functional Antibodies against Five Enterotoxigenic <i>Escherichia coli</i> Adhesins (CS7, CS12, CS14, CS17, and CS21) but Not Enterotoxins (LT and STa)
by: Siqi Li, et al.
Published: (2023-10-01)
by: Siqi Li, et al.
Published: (2023-10-01)
Application of Recombinant Lactic Acid Bacteria (LAB) Live Vector Oral Vaccine in the Prevention of F4+ Enterotoxigenic <i>Escherichia coli</i>
by: Jiangxu Yu, et al.
Published: (2024-03-01)
by: Jiangxu Yu, et al.
Published: (2024-03-01)
Immune Response after Skin Delivery of a Recombinant Heat-Labile Enterotoxin B Subunit of Enterotoxigenic <i>Escherichia coli</i> in Mice
by: Melibea Berzosa, et al.
Published: (2022-01-01)
by: Melibea Berzosa, et al.
Published: (2022-01-01)
Heterologous prime-boost immunization of two-component vaccine candidate PWDVax protected pigs against F18 enterotoxigenic Escherichia coli post-weaning diarrhea
by: Chongyang Zhang, et al.
Published: (2025-04-01)
by: Chongyang Zhang, et al.
Published: (2025-04-01)
Serological and virulence factors analysis of Escherichia coli isolates causing post-weaning diarrhea in intensive pig farms
by: JIANG Zhong-qi, et al.
Published: (2006-09-01)
by: JIANG Zhong-qi, et al.
Published: (2006-09-01)
Optimization of Enterotoxigenic <i>Escherichia coli</i> (ETEC) Outer Membrane Vesicles Production and Isolation Method for Vaccination Purposes
by: Melibea Berzosa, et al.
Published: (2023-08-01)
by: Melibea Berzosa, et al.
Published: (2023-08-01)
Seroprevalence Study of Conserved Enterotoxigenic <i>Escherichia coli</i> Antigens in Globally Diverse Populations
by: Frederick Matthew Kuhlmann, et al.
Published: (2023-08-01)
by: Frederick Matthew Kuhlmann, et al.
Published: (2023-08-01)
Evidence of pathogens associated with travelers’ diarrhea in Thailand: a systematic review
by: Wanida Mala, et al.
Published: (2025-04-01)
by: Wanida Mala, et al.
Published: (2025-04-01)
Immunogenicity and preclinical efficacy characterization of ShecVax, a combined vaccine against Shigella and enterotoxigenic Escherichia coli
by: Siqi Li, et al.
Published: (2025-06-01)
by: Siqi Li, et al.
Published: (2025-06-01)
Adjuvant effect of enterotoxigenic Escherichia coli (ETEC) double-mutant heat-labile toxin (dmLT) on systemic immunogenicity induced by the CFA/I/II/IV MEFA ETEC vaccine: Dose-related enhancement of antibody responses to seven ETEC adhesins (CFA/I, CS1-CS6)
by: Hyesuk Seo, et al.
Published: (2020-02-01)
by: Hyesuk Seo, et al.
Published: (2020-02-01)
Oral Immunogenicity of Enterotoxigenic <i>Escherichia coli</i> Outer Membrane Vesicles Encapsulated into Zein Nanoparticles Coated with a Gantrez<sup>®</sup> AN–Mannosamine Polymer Conjugate
by: Melibea Berzosa, et al.
Published: (2022-01-01)
by: Melibea Berzosa, et al.
Published: (2022-01-01)
Enterotoxigenic and Antimicrobic Susceptibility Profile of <i>Staphylococcus aureus</i> Isolates from Fresh Cheese in Croatia
by: Ivana Ljevaković-Musladin, et al.
Published: (2023-12-01)
by: Ivana Ljevaković-Musladin, et al.
Published: (2023-12-01)
In Silico Prediction, Molecular Docking and Dynamics Studies of Steroidal Alkaloids of <i>Holarrhena pubescens</i> Wall. ex G. Don to Guanylyl Cyclase C: Implications in Designing of Novel Antidiarrheal Therapeutic Strategies
by: Neha Gupta, et al.
Published: (2021-07-01)
by: Neha Gupta, et al.
Published: (2021-07-01)
MecVax supplemented with CFA MEFA-II induces functional antibodies against 12 adhesins (CFA/I, CS1–CS7, CS12, CS14, CS17, and CS21) and 2 toxins (STa, LT) of enterotoxigenic Escherichia coli (ETEC)
by: Chongyang Zhang, et al.
Published: (2024-04-01)
by: Chongyang Zhang, et al.
Published: (2024-04-01)
A Novel Multiepitope Fusion Antigen as a Vaccine Candidate for the Prevention of Enterotoxigenic <i>E. coli</i>-Induced Calf Diarrhea
by: Haoyun Zhang, et al.
Published: (2024-04-01)
by: Haoyun Zhang, et al.
Published: (2024-04-01)
Metallo-Glycodendrimeric Materials against Enterotoxigenic <i>Escherichia coli</i>
by: Aly El Riz, et al.
Published: (2024-05-01)
by: Aly El Riz, et al.
Published: (2024-05-01)
Heat-Stable Enterotoxin Secretions Assessed via ICP-MS Reveal Iron-Mediated Regulation of Virulence in CFA/I- and CS6-Expressing ETEC Isolates
by: Ian E. Hollifield, et al.
Published: (2023-02-01)
by: Ian E. Hollifield, et al.
Published: (2023-02-01)
Enterotoxigenic Escherichia coli: intestinal pathogenesis mechanisms and colonization resistance by gut microbiota
by: Yucheng Zhang, et al.
Published: (2022-12-01)
by: Yucheng Zhang, et al.
Published: (2022-12-01)
An LTB-entrapped protein in PLGA nanoparticles preserves against enterotoxin of enterotoxigenic Escherichia coli
by: Emad Kordbacheh, et al.
Published: (2018-05-01)
by: Emad Kordbacheh, et al.
Published: (2018-05-01)
Dietary Fe-Gly supplementation attenuates enterotoxigenic Escherichia coli (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets
by: Qing Gao, et al.
Published: (2025-01-01)
by: Qing Gao, et al.
Published: (2025-01-01)
Detection of Heat-labile Toxin and Evaluation of Antibiotic Resistance in Enterotoxigenic Escherichia Coli Isolated from Samples of Diarrhea in Children below 5 Years Old in Sari
by: Esmaeil Fattahi, et al.
Published: (2018-05-01)
by: Esmaeil Fattahi, et al.
Published: (2018-05-01)
Genotypic characterization of Egypt enterotoxigenic Escherichia coli isolates expressing coli surface antigen 6
by: Atef M El-Gendy, et al.
Published: (2013-02-01)
by: Atef M El-Gendy, et al.
Published: (2013-02-01)
Production of monoclonal antibody of heat-labile toxin A subunit to identify enterotoxigenic Escherichia coli by epitope mapping using synthetic peptides
by: Jun-Young Park, et al.
Published: (2023-05-01)
by: Jun-Young Park, et al.
Published: (2023-05-01)
A Perspective on the Strategy for Advancing ETVAX<sup>®</sup>, An Anti-ETEC Diarrheal Disease Vaccine, into a Field Efficacy Trial in Gambian Children: Rationale, Challenges, Lessons Learned, and Future Directions
by: M. Jahangir Hossain, et al.
Published: (2023-12-01)
by: M. Jahangir Hossain, et al.
Published: (2023-12-01)
Feasibility of avian antibodies as prophylaxis against enterotoxigenic escherichia coli colonization
by: Kyle Brumfield, et al.
Published: (2022-10-01)
by: Kyle Brumfield, et al.
Published: (2022-10-01)
ArcA positively regulates the expression of virulence genes and contributes to virulence of porcine Shiga toxin-producing enterotoxigenic Escherichia coli
by: Fengwei Jiang, et al.
Published: (2023-12-01)
by: Fengwei Jiang, et al.
Published: (2023-12-01)
Safety and immunogenicity of a recombinant double-mutant heat-labile toxin derived from enterotoxigenic Escherichia coli in healthy Bangladeshi adults delivered by three different routes
by: Taufiqur Rahman Bhuiyan, et al.
Published: (2025-07-01)
by: Taufiqur Rahman Bhuiyan, et al.
Published: (2025-07-01)
Intestinal microbiota mediates Enterotoxigenic Escherichia coli-induced diarrhea in piglets
by: Peng Bin, et al.
Published: (2018-12-01)
by: Peng Bin, et al.
Published: (2018-12-01)
Similar Items
-
Development of an enterotoxigenic Escherichia coli vaccine based on the heat-stable toxin
by: Ephrem Debebe Zegeye, et al.
Published: (2019-06-01) -
Impact of the <i>Escherichia coli</i> Heat-Stable Enterotoxin b (STb) on Gut Health and Function
by: Shahnawaz Butt, et al.
Published: (2020-12-01) -
Enterotoxigenic <i>Escherichia coli</i> Heat-Stable Toxin and Ebola Virus Delta Peptide: Similarities and Differences
by: Lilia I. Melnik, et al.
Published: (2022-01-01) -
Co-administered Tag-Less Toxoid Fusion 3xSTaN12S-mnLTR192G/L211A and CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) Induce Neutralizing Antibodies to 7 Adhesins (CFA/I, CS1-CS6) and Both Enterotoxins (LT, STa) of Enterotoxigenic Escherichia coli (ETEC)
by: Qiangde Duan, et al.
Published: (2018-06-01) -
Designing Vaccines to Neutralize Effective Toxin Delivery by Enterotoxigenic Escherichia coli
by: James M. Fleckenstein, et al.
Published: (2014-06-01)
