Function and Regulation of Histone H3 Lysine-4 Methylation During Oocyte Meiosis and Maternal-to-Zygotic Transition

During oogenesis and fertilization, histone lysine methyltransferases (KMTs) and histone lysine demethylases (KDMs) tightly regulate the methylation of histone H3 on lysine-4 (H3K4me) by adding and removing methyl groups, respectively. Female germline-specific conditional knockout approaches that ab...

Full description

Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Qian-Qian Sha, Jue Zhang, Heng-Yu Fan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Subjects:	genome reprogramming histone modification histone methyl transferase early embryo zygote germ cell
Online Access:	https://www.frontiersin.org/article/10.3389/fcell.2020.597498/full