Invasive Vulval Paget’s disease treated with primary radiotherapy: A rare case report and literature review

Extramammary Vulval Paget’s Disease (VPD) is rare neoplasm of post-menopausal women. In relatively young perimenopausal patients, it can cause both diagnostic dilemma and therapeutic challenges. Majority of VPD is of non-invasive variety. Among invasive Paget’s disease, only 20% cases show invasion...

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Bibliographic Details
Published in:Gynecologic Oncology Reports
Main Authors: Avir Sarkar, S.C. Saha, Pooja Sikka, Neha Kumari, Pranab Dey, Bhavana Rai
Format: Article
Language:English
Published: Elsevier 2020-11-01
Subjects:
Paget’s disease
Vulva
Radiotherapy
Neoplasm
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578920301405
Description
Summary:Extramammary Vulval Paget’s Disease (VPD) is rare neoplasm of post-menopausal women. In relatively young perimenopausal patients, it can cause both diagnostic dilemma and therapeutic challenges. Majority of VPD is of non-invasive variety. Among invasive Paget’s disease, only 20% cases show invasion more than 1 mm. The present report describes a unique case of an invasive extra-mammary VPD with depth of invasion more than 4 mm presenting at a relatively young perimenopausal lady. Only 14 cases of VPD has been treated with primary radiotherapy in literature till date. We report this case to be the 15th case where radiotherapy was solely used to treat an invasive VPD.
ISSN:2352-5789

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