Inside the impulsive brain: a narrative review on the role of neurobiological, hormonal and genetic factors influencing impulsivity in psychiatric disorders

Abstract This abstract delves into the intricate nature of impulsivity and its ramifications across psychiatric disorders, leveraging advancements in neuroimaging and psychological studies. It elucidates diverse facets of impulsivity, encompassing response, choice, and tendencies, emphasizing its pi...

Full description

Bibliographic Details
Published in:	The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Main Authors:	Hannah Raji, Susha Dinesh, Sameer Sharma
Format:	Article
Language:	English
Published:	SpringerOpen 2025-01-01
Subjects:	Cortisol regulation Ventromedial prefrontal cortex Nucleus accumbens core Dopamine axis Serotonin systems Dopamine modulator
Online Access:	https://doi.org/10.1186/s41983-024-00930-9

Similar Items

Early Life Adversity Alters the Developmental Profiles of Addiction-Related Prefrontal Cortex Circuitry
by: Susan L. Andersen, et al.
Published: (2013-02-01)

The Role of Mesostriatal Dopamine System and Corticostriatal Glutamatergic Transmission in Chronic Pain
by: Barbara Ziółkowska
Published: (2021-10-01)

Subregion specific monoaminergic signaling in the female rat striatum during nicotine abstinence
by: Erika Lucente, et al.
Published: (2024-12-01)

Prefrontal Dopamine in Flexible Adaptation to Environmental Changes: A Game for Two Players
by: Emanuele Claudio Latagliata, et al.
Published: (2023-11-01)

Schizophrenia Patients Show Largely Similar Salience Signaling Compared to Healthy Controls in an Observational Task Environment
by: Adam J. Culbreth, et al.
Published: (2021-12-01)

Chronic Red Bull Consumption during Adolescence: Effect on Mesocortical and Mesolimbic Dopamine Transmission and Cardiovascular System in Adult Rats
by: Romina Vargiu, et al.
Published: (2021-06-01)

Impact of Vortioxetine on Synaptic Integration in Prefrontal-Subcortical Circuits: Comparisons with Escitalopram
by: Shreaya Chakroborty, et al.
Published: (2017-10-01)

Monoaminergic Modulation of Learning and Cognitive Function in the Prefrontal Cortex
by: Natalie Boyle, et al.
Published: (2024-09-01)

Identification of photoperiod as a regulator of dopamine-mediated behavior in female mice
by: Beimnet B. Kassaye, et al.
Published: (2025-11-01)

Role of dopamine receptor heteromerization in preclinical models of addiction and other psychiatric disorders
by: Adèle Vilette, et al.
Published: (2025-04-01)

Nucleus Accumbens Dopamine Levels Fluctuate Across Different States of Consciousness Under Sevoflurane Anesthesia
by: Weiwei Bao, et al.
Published: (2025-08-01)

Editorial: Brain reward and aversion circuits: progress review on current and future breakthroughs
by: Dan P. Covey, et al.
Published: (2025-06-01)

Physiological neuroadaptations in prefrontal cortical regulation of abstinence and cue-induced relapse to cocaine seeking
by: Saurabh S. Kokane, et al.
Published: (2025-12-01)

The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats
by: Paolo Campus, et al.
Published: (2019-09-01)

Semaglutide reduces alcohol intake and relapse-like drinking in male and female ratsResearch in context
by: Cajsa Aranäs, et al.
Published: (2023-07-01)

Neurobiology of hedonic tone: the relationship between treatment-resistant depression, attention-deficit hyperactivity disorder, and substance abuse
by: Sternat T, et al.
Published: (2016-08-01)

Acupuncture and oxytocinergic system: The promising treatment for autism
by: Su Tangfeng, et al.
Published: (2021-02-01)

Attenuation of Basal Gastric Acid Secretion Following the Blockade of Hypothalamic Ventromedial D2 Receptors in Rats
by: Maedeh Ghasemi, et al.
Published: (2018-08-01)

Gestational stress disrupts dopamine and oxytocin signaling in the postpartum reward system of rats: implications for mood, motivation and mothering
by: Achikam Haim, et al.
Published: (2025-01-01)

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius
by: Christian E. Edvardsson, et al.
Published: (2024-08-01)

Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage
by: Ana Paula S. Dornellas, et al.
Published: (2021-01-01)

Pharmacological effects of nicotine salts on dopamine release in the nucleus accumbens
by: Xiaonan Li, et al.
Published: (2023-09-01)

Effects of age and sex on photoperiod modulation of nucleus accumbens monoamine content and release in adolescence and adulthood
by: Alexis N. Jameson, et al.
Published: (2024-05-01)

Dopamine D2-Subtype Receptors Outside the Blood-Brain Barrier Mediate Enhancement of Mesolimbic Dopamine Release and Conditioned Place Preference by Intravenous Dopamine
by: J. Daniel Obray, et al.
Published: (2022-07-01)

Restoration of the Activity of the Prefrontal Cortex to the Nucleus Accumbens Core Pathway Relieves Fentanyl-Induced Hyperalgesia in Male Rats
by: Luo Q, et al.
Published: (2024-03-01)

Effect of environmentally relevant concentrations of estrogens on the aggressive response of male zebrafish
by: Ying–Ying Zhang, et al.
Published: (2025-07-01)

Expression of Dopamine-Related Genes in Four Human Brain Regions
by: Ansley Grimes Stanfill, et al.
Published: (2020-08-01)

Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction
by: Wan‐Kun Gong, et al.
Published: (2025-04-01)

Control of parallel hippocampal output pathways by amygdalar long-range inhibition
by: Rawan AlSubaie, et al.
Published: (2021-11-01)

Phasic activation of ventral tegmental neurons increases response and pattern similarity in prefrontal cortex neurons
by: Motoko Iwashita
Published: (2014-09-01)

Optimizing Chronotherapy in Psychiatric Care: The Impact of Circadian Rhythms on Medication Timing and Efficacy
by: Cezar-Ivan Colita, et al.
Published: (2024-11-01)

The involvement of GABA-rho receptors in regulating ethanol-induced elevation of dopamine, glycine and taurine within the nucleus accumbens of Wistar rats
by: Davide Cadeddu, et al.
Published: (2025-10-01)

The superoxide dismutase mimetic TEMPOL modulates nicotine-induced hyperlocomotor activity and nicotine-taking behavior in male rats
by: Kyung Oh Jeon, et al.
Published: (2025-02-01)

Examining the role of the photopigment melanopsin in the striatal dopamine response to light
by: L. Sofia Gonzalez, et al.
Published: (2025-04-01)

A Neurological Comparison Between Addiction to Social Media and Drug
by: somayeh Rasouli, et al.
Published: (2024-01-01)

MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro
by: F Woodward Hopf, et al.
Published: (2013-04-01)

The central GLP-1: implications for food and drug reward
by: Karolina Patrycja Skibicka
Published: (2013-10-01)

Neural Circuitry of Salience and Reward Processing in Psychosis
by: James P. Kesby, et al.
Published: (2023-01-01)

Heads for learning, tails for memory: Reward, reinforcement and a role of dopamine in determining behavioural relevance across multiple timescales
by: Mathieu eBaudonnat, et al.
Published: (2013-10-01)

Antidepressant-like Activity of Patchouli Oil var. Tapak Tuan (<i>Pogostemon cablin</i> Benth) via Elevated Dopamine Level: A Study Using Rat Model
by: Puji Astuti, et al.
Published: (2022-05-01)