那格列奈对2型糖尿病患者空腹游离脂肪酸的影响

【目的】探讨那格列奈对初诊2型糖尿病患者空腹游离脂肪酸的影响。【方法】42例从未进行降糖及降脂药物治疗的初诊2型糖尿病患者，随机分为那格列奈组及瑞格列奈组各21例，测定空腹游离脂肪酸（FFA）及空腹血糖（FPG）、标准餐后2h血糖（2hPG）、血脂谱，次日行静脉葡萄糖胰岛素释放试验（IVG-IRT）后，分组给予那格列奈60～90mg或瑞格列奈0．5～1．0mg，双盲治疗12周后，重复前述检查。【结果】37例完成试验，那格列奈组（18例）空腹FFA从（0．47±0．18）mmol／L下降到（0．36±0．16）mmol／L，平均下降（0．11±0．21）mmol／L（P〈0．05），瑞格列奈组（...

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Bibliographic Details
Published in:	Zhongshan Daxue xuebao. Yixue kexue ban
Main Authors:	王甫能, 廖志红, 胡国亮, 李延兵, 欧香忠, 翁建平
Format:	Article
Language:	Chinese
Published:	Editorial Office of Journal of Sun Yat-sen University 2006-01-01
Subjects:	那格列奈瑞格列奈 2型糖尿病游离脂肪酸
Online Access:	http://xuebaoyx.sysu.edu.cn/zh/article/43582863/

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