Astrocyte-derived GDNF is a potent inhibitor of microglial activation

Neuroinflammation is recognized as a major factor in Parkinson's disease (PD) pathogenesis and increasing evidence propose that microglia is the main source of inflammation contributing to the dopaminergic degeneration observed in PD. Several studies suggest that astrocytes could act as physiol...

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Bibliographic Details
Published in:	Neurobiology of Disease
Main Authors:	Sandra Moreira Rocha, Ana Clara Cristovão, Filipa Lopes Campos, Carla Pais Fonseca, Graça Baltazar
Format:	Article
Language:	English
Published:	Elsevier 2012-09-01
Subjects:	Neuroinflammation Neurotrophic factors Parkinson's disease Microglia Substantia nigra GDNF
Online Access:	http://www.sciencedirect.com/science/article/pii/S096999611200160X

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