Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature

It has been estimated that approximately one in seven of all global suicides is due to pesticide self-poisoning, mostly in rural areas of developing countries. Organophosphorus (OP) compounds are a group of pesticides exerting their toxicological effects through non-reversible inhibition of the enzy...

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Published in:Toxics
Main Authors: Angela Simonelli, Anna Carfora, Pascale Basilicata, Bruno Liguori, Pasquale Mascolo, Fabio Policino, Massimo Niola, Carlo Pietro Campobasso
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Subjects:
Online Access:https://www.mdpi.com/2305-6304/10/5/205
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author Angela Simonelli
Anna Carfora
Pascale Basilicata
Bruno Liguori
Pasquale Mascolo
Fabio Policino
Massimo Niola
Carlo Pietro Campobasso
author_facet Angela Simonelli
Anna Carfora
Pascale Basilicata
Bruno Liguori
Pasquale Mascolo
Fabio Policino
Massimo Niola
Carlo Pietro Campobasso
author_sort Angela Simonelli
collection DOAJ
container_title Toxics
description It has been estimated that approximately one in seven of all global suicides is due to pesticide self-poisoning, mostly in rural areas of developing countries. Organophosphorus (OP) compounds are a group of pesticides exerting their toxicological effects through non-reversible inhibition of the enzyme acetylcholinesterase (AChE). Among these compounds, phorate (thimet) is one of the most dangerous compounds, the use of which is restricted in many countries. A case of intentional suicide after phorate ingestion in a 24-year-old Bengali male is described. This is the second case of suicidal ingestion of phorate reported in the forensic literature, and the first presenting complete toxicological findings.
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spelling doaj-art-e7d0d3cbc3d34c2dbfb93227266bb7d92025-08-19T22:32:53ZengMDPI AGToxics2305-63042022-04-0110520510.3390/toxics10050205Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of LiteratureAngela Simonelli0Anna Carfora1Pascale Basilicata2Bruno Liguori3Pasquale Mascolo4Fabio Policino5Massimo Niola6Carlo Pietro Campobasso7Department of Advanced Biomedical Science, Legal Medicine Section, University of Naples “Federico II”, Via S. Pansini, 5, 80138 Napoli, ItalyForensic Toxicology Unit, Department of Experimental Medicine, University of Campania “L. Vanvitelli”, Via L. Armanni, 5, 80138 Napoli, ItalyDepartment of Advanced Biomedical Science, Legal Medicine Section, University of Naples “Federico II”, Via S. Pansini, 5, 80138 Napoli, ItalyDepartment of Experimental Medicine, Institute of Legal Medicine, University of Campania “L. Vanvitelli”, Via L. Armanni, 5, 80138 Napoli, ItalyDepartment of Experimental Medicine, Institute of Legal Medicine, University of Campania “L. Vanvitelli”, Via L. Armanni, 5, 80138 Napoli, ItalyDepartment of Advanced Biomedical Science, Legal Medicine Section, University of Naples “Federico II”, Via S. Pansini, 5, 80138 Napoli, ItalyDepartment of Advanced Biomedical Science, Legal Medicine Section, University of Naples “Federico II”, Via S. Pansini, 5, 80138 Napoli, ItalyForensic Toxicology Unit, Department of Experimental Medicine, University of Campania “L. Vanvitelli”, Via L. Armanni, 5, 80138 Napoli, ItalyIt has been estimated that approximately one in seven of all global suicides is due to pesticide self-poisoning, mostly in rural areas of developing countries. Organophosphorus (OP) compounds are a group of pesticides exerting their toxicological effects through non-reversible inhibition of the enzyme acetylcholinesterase (AChE). Among these compounds, phorate (thimet) is one of the most dangerous compounds, the use of which is restricted in many countries. A case of intentional suicide after phorate ingestion in a 24-year-old Bengali male is described. This is the second case of suicidal ingestion of phorate reported in the forensic literature, and the first presenting complete toxicological findings.https://www.mdpi.com/2305-6304/10/5/205phoratesuicidal ingestionpesticides
spellingShingle Angela Simonelli
Anna Carfora
Pascale Basilicata
Bruno Liguori
Pasquale Mascolo
Fabio Policino
Massimo Niola
Carlo Pietro Campobasso
Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
phorate
suicidal ingestion
pesticides
title Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
title_full Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
title_fullStr Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
title_full_unstemmed Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
title_short Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
title_sort suicide by pesticide phorate ingestion case report and review of literature
topic phorate
suicidal ingestion
pesticides
url https://www.mdpi.com/2305-6304/10/5/205
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