Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis
There are numerous types of pathological changes in human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND), including apoptosis of neurons. HIV-1 transactivator of transcription (Tat) protein, which is encoded by HIV-1, may promote apoptosis in HAND. Forkhead box O3 (FOXO3) is...
| 发表在: | Frontiers in Neuroscience |
|---|---|
| Main Authors: | Huaqian Dong, Xiang Ye, Li Zhong, Jinhong Xu, Jinhua Qiu, Jun Wang, Yiming Shao, Huiqin Xing |
| 格式: | 文件 |
| 语言: | 英语 |
| 出版: |
Frontiers Media S.A.
2019-02-01
|
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/article/10.3389/fnins.2019.00044/full |
相似书籍
Corrigendum: Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis
由: Huaqian Dong, et al.
出版: (2022-01-01)
由: Huaqian Dong, et al.
出版: (2022-01-01)
HIV, Tat and dopamine transmission
由: Peter J. Gaskill, et al.
出版: (2017-09-01)
由: Peter J. Gaskill, et al.
出版: (2017-09-01)
The role of HIV Tat protein in HIV-related cardiovascular diseases
由: Yanan Jiang, et al.
出版: (2018-05-01)
由: Yanan Jiang, et al.
出版: (2018-05-01)
HIV-1 Tat alters neuronal intrinsic excitability
由: Walter Francesconi, et al.
出版: (2018-05-01)
由: Walter Francesconi, et al.
出版: (2018-05-01)
Signatures of HIV-1 subtype B and C Tat proteins and their effects in the neuropathogenesis of HIV-associated neurocognitive impairments
由: Monray E. Williams, et al.
出版: (2020-03-01)
由: Monray E. Williams, et al.
出版: (2020-03-01)
The role of Tat in HIV latency and reactivation
由: David M. Margolis, et al.
出版: (2025-08-01)
由: David M. Margolis, et al.
出版: (2025-08-01)
HIV-1 Tat is present in the serum of people living with HIV-1 despite viral suppression
由: Anna Shmakova, et al.
出版: (2024-05-01)
由: Anna Shmakova, et al.
出版: (2024-05-01)
HIV-1 Tat neurotoxicity: A model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes
由: Lokesh Agrawal, et al.
出版: (2012-02-01)
由: Lokesh Agrawal, et al.
出版: (2012-02-01)
HIV Tat as a latency reversing agent: turning the tables on viral persistence
由: Bridget M. Fisher, et al.
出版: (2025-04-01)
由: Bridget M. Fisher, et al.
出版: (2025-04-01)
HIV-Tat upregulates the expression of senescence biomarkers in CD4+ T-cells
由: Víctor Casanova, et al.
出版: (2025-04-01)
由: Víctor Casanova, et al.
出版: (2025-04-01)
Targeting Tat–TAR RNA Interaction for HIV-1 Inhibition
由: Awadh Alanazi, et al.
出版: (2021-10-01)
由: Awadh Alanazi, et al.
出版: (2021-10-01)
Tat-specific antibodies associated with better HIV-associated motor function
由: Catarina E. Hioe, et al.
出版: (2025-08-01)
由: Catarina E. Hioe, et al.
出版: (2025-08-01)
Neurocognitive dysfunction among HIV positive patients using International HIV dementia scale
由: Basavaprabhu Achappa
出版: (2014-05-01)
由: Basavaprabhu Achappa
出版: (2014-05-01)
Tat-Based Therapies as an Adjuvant for an HIV-1 Functional Cure
由: Hongping Jin, et al.
出版: (2020-04-01)
由: Hongping Jin, et al.
出版: (2020-04-01)
HIV-1 Tat enhances purinergic P2Y4 receptor signaling to mediate inflammatory cytokine production and neuronal damage via PI3K/Akt and ERK MAPK pathways
由: Feng Zhou, et al.
出版: (2019-04-01)
由: Feng Zhou, et al.
出版: (2019-04-01)
Intracellular HIV-1 Tat regulator induces epigenetic changes in the DNA methylation landscape
由: Andrea Rodríguez-Agustín, et al.
出版: (2025-03-01)
由: Andrea Rodríguez-Agustín, et al.
出版: (2025-03-01)
Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive Disorders
由: Kim T. Gurwitz, et al.
出版: (2017-05-01)
由: Kim T. Gurwitz, et al.
出版: (2017-05-01)
HIV heart inflammation is mediated by HIV infected myeloid cells, HIV-tat secretion, and aberrant function of Connexin43-containing channels
由: David Ajasin, et al.
出版: (2026-03-01)
由: David Ajasin, et al.
出版: (2026-03-01)
HIV Tat‐Stimulated Microglial Extracellular Vesicles Are Enriched for Ferroptosis Mediators: Role of Dysregulated Autophagy
由: Seema Singh, et al.
出版: (2026-06-01)
由: Seema Singh, et al.
出版: (2026-06-01)
Asymptomatic neurocognitive disorders in patients infected by HIV: fact or fiction?
由: Torti Carlo, et al.
出版: (2011-12-01)
由: Torti Carlo, et al.
出版: (2011-12-01)
HIV latency reversing agents act through Tat post translational modifications
由: Georges Khoury, et al.
出版: (2018-05-01)
由: Georges Khoury, et al.
出版: (2018-05-01)
Extracellular HIV-1 Tat Mediates Increased Glutamate in the CNS Leading to Onset of Senescence and Progression of HAND
由: Jamie Marino, et al.
出版: (2020-06-01)
由: Jamie Marino, et al.
出版: (2020-06-01)
Impact of subtype C-specific amino acid variants on HIV-1 Tat-TAR interaction: insights from molecular modelling and dynamics
由: Piwai T. Gotora, et al.
出版: (2024-06-01)
由: Piwai T. Gotora, et al.
出版: (2024-06-01)
Neurocognitive Impairment in ART-Experienced People Living with HIV: An Analysis of Clinical Risk Factors, Injection Drug Use, and the sCD163
由: Syed Zaryab Ahmed, et al.
出版: (2025-09-01)
由: Syed Zaryab Ahmed, et al.
出版: (2025-09-01)
Novel role of mortalin in attenuating HIV-1 Tat-mediated astrogliosis
由: Priyanka, et al.
出版: (2020-09-01)
由: Priyanka, et al.
出版: (2020-09-01)
Antiretroviral therapy initiated during acute infection in women with HIV-1 clade C reduces anti-Tat antibody production and lowers CD8+ T cell activation
由: Thandeka I. Kubheka, et al.
出版: (2025-06-01)
由: Thandeka I. Kubheka, et al.
出版: (2025-06-01)
Glutathione in HIV-Associated Neurocognitive Disorders
由: Thomas Erdos, et al.
出版: (2024-05-01)
由: Thomas Erdos, et al.
出版: (2024-05-01)
Prevalence of neurocognitive disorders and depression in a Brazilian HIV population
由: Flávio Trentin Troncoso, et al.
出版: (2015-08-01)
由: Flávio Trentin Troncoso, et al.
出版: (2015-08-01)
Prevention of HIV-1 TAT Protein-Induced Peripheral Neuropathy and Mitochondrial Disruption by the Antimuscarinic Pirenzepine
由: May Madi Han, et al.
出版: (2021-06-01)
由: May Madi Han, et al.
出版: (2021-06-01)
HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation
由: Mayur Doke, et al.
出版: (2021-09-01)
由: Mayur Doke, et al.
出版: (2021-09-01)
Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors
由: Susana Valente, et al.
出版: (2012-11-01)
由: Susana Valente, et al.
出版: (2012-11-01)
Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroHIV
由: Indira S. Harahap-Carrillo, et al.
出版: (2025-02-01)
由: Indira S. Harahap-Carrillo, et al.
出版: (2025-02-01)
Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat
由: Alexis F. League, et al.
出版: (2021-08-01)
由: Alexis F. League, et al.
出版: (2021-08-01)
HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia
由: Giovanni Sarnelli, et al.
出版: (2018-03-01)
由: Giovanni Sarnelli, et al.
出版: (2018-03-01)
Psychiatric Manifestations in a Patient with HIV-Associated Neurocognitive Symptoms and Cryptococcal Meningitis
由: Prabhakar C Holikatti, et al.
出版: (2012-01-01)
由: Prabhakar C Holikatti, et al.
出版: (2012-01-01)
A Rationale and Approach to the Development of Specific Treatments for HIV Associated Neurocognitive Impairment
由: Aaron Scanlan, et al.
出版: (2022-11-01)
由: Aaron Scanlan, et al.
出版: (2022-11-01)
HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods
由: Paolo Carloni, et al.
出版: (2012-08-01)
由: Paolo Carloni, et al.
出版: (2012-08-01)
Manganese-induced apoptosis through the ROS-activated JNK/FOXO3a signaling pathway in CTX cells, a model of rat astrocytes
由: Wan-He Li, et al.
出版: (2023-09-01)
由: Wan-He Li, et al.
出版: (2023-09-01)
HIV-1 Tat-mediated microglial ferroptosis involves the miR-204–ACSL4 signaling axis
由: Muthukumar Kannan, et al.
出版: (2023-06-01)
由: Muthukumar Kannan, et al.
出版: (2023-06-01)
17⍺-Estradiol Protects against HIV-1 Tat-Induced Endolysosome Dysfunction and Dendritic Impairments in Neurons
由: Gaurav Datta, et al.
出版: (2023-03-01)
由: Gaurav Datta, et al.
出版: (2023-03-01)
相似书籍
-
Corrigendum: Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis
由: Huaqian Dong, et al.
出版: (2022-01-01) -
HIV, Tat and dopamine transmission
由: Peter J. Gaskill, et al.
出版: (2017-09-01) -
The role of HIV Tat protein in HIV-related cardiovascular diseases
由: Yanan Jiang, et al.
出版: (2018-05-01) -
HIV-1 Tat alters neuronal intrinsic excitability
由: Walter Francesconi, et al.
出版: (2018-05-01) -
Signatures of HIV-1 subtype B and C Tat proteins and their effects in the neuropathogenesis of HIV-associated neurocognitive impairments
由: Monray E. Williams, et al.
出版: (2020-03-01)
