<i>Bacopa monnieri</i> and Their Bioactive Compounds Inferred Multi-Target Treatment Strategy for Neurological Diseases: A Cheminformatics and System Pharmacology Approach

Neurological diseases (NDs), especially Alzheimer’s and Spinocerebellar ataxia (SCA), can severely cause biochemical abnormalities in the brain, spinal cord and other nerves of human beings. Their ever-increasing prevalence has led to a demand for new drug development. Indian traditional and Ayurved...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Biomolecules
المؤلفون الرئيسيون:	Rajendran Jeyasri, Pandiyan Muthuramalingam, Vellaichami Suba, Manikandan Ramesh, Jen-Tsung Chen
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2020-04-01
الموضوعات:	Alzheimer’s disease <i>Bacopa monnieri</i> bioactive compounds cheminformatics neurological diseases spinocerebellar ataxia
الوصول للمادة أونلاين:	https://www.mdpi.com/2218-273X/10/4/536

مواد مشابهة

Bioaccumulation Pattern of Mercury in Bacopa monnieri (L.) Pennell
حسب: Hussain K, وآخرون
منشور في: (2012-05-01)

Heavy metal accumulation potential and medicinal property of Bacopa monnieri - a paradox
حسب: Nabeesa Salim, وآخرون
منشور في: (2011-12-01)

Propagation of water hyssop ( Bacopa monnieri L.) in vitro
حسب: Haleemah J. AL-Arady, وآخرون
منشور في: (2021-11-01)

Bio-Computational Evaluation of Compounds of Bacopa Monnieri as a Potential Treatment for Schizophrenia
حسب: Ali H. Alharbi
منشور في: (2022-10-01)

Exploiting Marker Genes for Reliable Botanical Authentication of <i>Bacopa monnieri</i> Products
حسب: Rita Biltes, وآخرون
منشور في: (2025-09-01)

Investigating the Neuroprotective and Cognitive-Enhancing Effects of <i>Bacopa monnieri</i>: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis
حسب: Luiz José Valotto Neto, وآخرون
منشور في: (2024-03-01)

Phytochemical analysis and synergistic memory enhancing effect of Bacopa monnieri with Piper nigrum
حسب: Sourabh Jain, وآخرون
منشور في: (2025-03-01)

Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review)
حسب: O.O. Nikitina, وآخرون
منشور في: (2024-10-01)

Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of <it>Bacopa monnieri </it>and Bacoside-A
حسب: Mathew Jobin, وآخرون
منشور في: (2012-02-01)

Strain specific Agrobacterium-mediated genetic transformation of Bacopa monnieri
حسب: Sheetal Yadav, وآخرون
منشور في: (2014-12-01)

Importance of high-quality evidence regarding the use of Bacopa monnieri in dementia
حسب: Ayush Agarwal, وآخرون
منشور في: (2023-03-01)

Action of Bacopa monnieri to antagonize cisplatin-induced emesis in Suncus murinus (house musk shrew)
حسب: Ihsan Ullah, وآخرون
منشور في: (2017-04-01)

Triterpenoid Saponins Investigation and Pharmacological (Cytotoxic and Antioxidant) Properties of Bacopa monnieri L. Cultivated in Iraq
حسب: Baghdad Science Journal
منشور في: (2018-06-01)

Comprehensive in vitro and in vivo evaluation of therapeutic potential of Bacopa-derived asiatic acid against a human oral pathogen Streptococcus mutans
حسب: Rajendran Jeyasri, وآخرون
منشور في: (2024-06-01)

Antioxidant, Anti-Inflammatory and Anti-Obesity Potential of Extracts Containing Phenols, Chlorophyll and Carotenoids from Mexican Wild Populations of <i>Bacopa monnieri</i> (L.) Wettst
حسب: Martha Martínez-García, وآخرون
منشور في: (2023-04-01)

Bacopa monnieri phytochemicals as promising BACE1 inhibitors for Alzheimer’s disease therapy
حسب: Satyam Sangeet, وآخرون
منشور في: (2025-04-01)

Synergism study of Bacopa monnieri and Piriformospora indica and its impact on Biomass and metabolite
حسب: Ashok V. Kharde, وآخرون
منشور في: (2023-11-01)

Recent Advances in Bacopa Monnieri Research: Neuroprotective Effects and Cognitive Decline Mitigation in Neurodegenerative Diseases with a Focus on Alzheimer’s and Parkinson’s Diseases
حسب: Mateusz Bychowski, وآخرون
منشور في: (2024-12-01)

Chemical-Genetic Interactions of <i>Bacopa monnieri</i> Constituents in Cells Deficient for the DNA Repair Endonuclease <i>RAD1</i> Appear Linked to Vacuolar Disruption
حسب: Chananya Huangteerakul, وآخرون
منشور في: (2021-02-01)

The Neuroprotective Effect of Bacopa monnieri against Pilocarpine Induced Status Epilepticus in Rats
حسب: Thanaporn Semphuet, وآخرون
منشور في: (2017-12-01)

Physiological and metabolic responses of Bacopa monnieri to salt-induced stress: implications for secondary metabolite elicitation
حسب: Worasitikulya Taratima, وآخرون
منشور في: (2025-07-01)

Prediction of In vitro organogenesis of Bacopa monnieri using artificial neural networks and regression models
حسب: Pavitra Viswanathan, وآخرون
منشور في: (2022-12-01)

Effect of different drying treatments on the physicochemical, functional, and antioxidant properties of Bacopa monnieri
حسب: Bhuban Padhiari, وآخرون
منشور في: (2021-12-01)

The Neurocognitive Effects of Bacopa monnieri and Cognitive Training on Markers of Brain Microstructure in Healthy Older Adults
حسب: Grace M. McPhee, وآخرون
منشور في: (2021-02-01)

Neuromodulatory role of Bacopa monnieri on oxidative stress induced by postnatal exposure to decabromodiphenyl ether (PBDE -209) in neonate and young female mice
حسب: Priya Verma, وآخرون
منشور في: (2014-04-01)

Bacopa monnieri: A promising herbal approach for neurodegenerative disease treatment supported by in silico and in vitro research
حسب: Shehla Shoukat, وآخرون
منشور في: (2023-11-01)

Secondary metabolite based anti-inflammatory, antioxidant activities, drug like properties, molecular docking enzyme inhibitors of selected medicinal plant Bacopa monnieri (L)Wettst
حسب: Sekar Govindarasu, وآخرون
منشور في: (2025-09-01)

Anti-asthmatic activity of Saudi herbal composites from plants Bacopa monnieri and Euphorbia hirta on Guinea pigs
حسب: Poyil Muhammad Musthafa, وآخرون
منشور في: (2022-05-01)

Revolutionizing nerve regeneration: A novel approach using polylactic acid/chitosan conduit with nerve-like cells and Bacopa monnieri in male rat model
حسب: Elham Hoveizi, وآخرون
منشور في: (2025-12-01)

Antibacterial Potential of <i>Bacopa monnieri</i> (L.) Wettst. and Its Bioactive Molecules against Uropathogens—An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections
حسب: Jyoti Mehta, وآخرون
منشور في: (2022-08-01)

Incorporating post-juicing spent residue of Bacopa monnieri in khakra is a promising approach towards circular economy with nutraceutical benefits
حسب: Shilpa B Jana, وآخرون
منشور في: (2025-12-01)

Integrated microscopic, HPTLC, and HRM analyses for differentiating Centella asiatica (L.) Urb., Bacopa monnieri (L.) Wettst, and Hydrocotyle umbellata L.
حسب: Manisorn Suksawat, وآخرون
منشور في: (2025-07-01)

Assessment of antimicrobial potential of green zinc oxide nanoparticles (ZnONPs) of Bacopa monnieri (L.) against clinical isolates of Escherichia coli
حسب: RIYA AHLAWAT, وآخرون
منشور في: (2025-10-01)

Discovery of Lipid Peroxidation Inhibitors from <i>Bacopa</i> Species Prioritized through Multivariate Data Analysis and Multi-Informative Molecular Networking
حسب: Tongchai Saesong, وآخرون
منشور في: (2019-08-01)

The Neuroprotective Effect of Bacopa monnieri against Pilocarpine Induced Status Epilepticus in Rats
حسب: Thanaporn Semphuet, وآخرون
منشور في: (2017-11-01)

“An exploratory randomized, double-blind, placebo- controlled trial protocol on combined Cognitive Behavioral Therapy and adjunct Brahmi (Bacopa monnieri) tablets in Premenstrual Syndrome management”
حسب: Shahina Khan, وآخرون
منشور في: (2025-09-01)

Repurposing Bacopa monnieri extracts containing Aquaporin-1 blockers to improve systemic oxidative stress: The BacOxy_I study
حسب: Hasnae Boughaleb, وآخرون
منشور في: (2025-06-01)

Nitrogen-doped carbon dots from Brahmi (Bacopa monnieri): Metal-free probe for efficient detection of metal pollutants and methylene blue dye degradation
حسب: Soman Kondetharayil, وآخرون
منشور في: (2025-07-01)

Bacopa Monnieri Protects the Directly Affected Organ as Well as Distant Organs Against I/R Injury by Modulating Anti-Inflammatory and Anti-Nitrosative Pathways in A Rat Model for Infra-Renal Aortic Occlusion
حسب: Hilal Ozlu, وآخرون
منشور في: (2021-08-01)

Standardized <i>Bacopa monnieri</i> Extract Ameliorates Learning and Memory Impairments through Synaptic Protein, Neurogranin, Pro-and Mature BDNF Signaling, and HPA Axis in Prenatally Stressed Rat Offspring
حسب: Karunanithi Sivasangari, وآخرون
منشور في: (2020-12-01)