pH-dependent interactions of coacervate-forming histidine-rich peptide with model lipid membranes

Peptide-based liquid droplets (coacervates) produced by spontaneous liquid-liquid phase separation (LLPS), have emerged as a promising class of drug delivery systems due to their high entrapping efficiency and the simplicity of their formulation. However, the detailed mechanisms governing their inte...

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Bibliographic Details
Published in:	Frontiers in Soft Matter
Main Authors:	Sushanth Gudlur, Filipe Viana Ferreira, Javier Shu Ming Ting, Carmen Domene, Syed Maricar, Anton P. Le Brun, Nageshwar Yepuri, Michael Moir, Robert Russell, Tamim Darwish, Ali Miserez, Marité Cárdenas
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	LLPS peptide coacervates neutron reflectivity membrane interaction model membrane molecular dynamic simulations
Online Access:	https://www.frontiersin.org/articles/10.3389/frsfm.2023.1339496/full

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