“It seems enormously valuable to me.” Perspectives of Dutch (potential) carriers of genetic FTD on onset-predictive biomarker testing

Abstract Background Onset-predictive biomarker tests (OPBT) in genetic frontotemporal dementia (FTD) may be used to recruit mutation carriers into preventive clinical trials before symptoms manifest. This would require disclosure of OPBT results to potential participants. This study investigates the...

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Bibliographic Details

Published in:	Alzheimer’s Research & Therapy
Main Authors:	Charlotte H. Graafland, Harro Seelaar, Jessica L. Panman, Lize C. Jiskoot, Tjitske Kleefstra, Jackie M. Poos, Edo Richard, Maartje H.N. Schermer, John C. van Swieten, Laura Donker Kaat, Eline M. Bunnik
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	Onset prediction Frontotemporal dementia Biomarker Ethics Genetic counselling Clinical trial recruitment
Online Access:	https://doi.org/10.1186/s13195-025-01749-z