Safety reporting in trials on glaucoma interventions registered in ClinicalTrials.gov and corresponding publications

Abstract Accurate, comprehensive, and consistent reporting of adverse events is of great importance for treatment decisions in clinical practice and patient safety. Aiming to evaluate the completeness and transparency of reported adverse events we conducted a retrospective analysis of completed clin...

Full description

Bibliographic Details
Published in:	Scientific Reports
Main Authors:	Ante Krešo, Marko Grahovac, Ljubo Znaor, Ana Marušić
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-11-01
Subjects:	Glaucoma treatment Reporting Adverse event Harms Safety ClinicalTrials.gov
Online Access:	https://doi.org/10.1038/s41598-024-79394-z

Similar Items

Characteristics of endodontic clinical trials registered in clinicalTrials.gov between 2000 and 2022
by: Gadde Praveen, et al.
Published: (2023-01-01)

Reporting of the safety from allergic rhinitis trials registered on ClinicalTrials.gov and in publications: An observational study
by: Ivan Paladin, et al.
Published: (2022-10-01)

Analyzing MASLD interventional clinical trial registration based on the ClinicalTrials.gov database
by: Hui Du, et al.
Published: (2025-03-01)

Completeness of intervention description in invasive cardiology trials: an observational study of ClinicalTrials.gov registry and corresponding publications
by: Viktoria Lišnić, et al.
Published: (2023-10-01)

Methodology of clinical trials on sodium-glucose cotransporter 2 inhibitors registered on ClinicalTrials.gov: a cross-sectional study
by: Fran Šaler, et al.
Published: (2024-07-01)

fMRI as an outcome measure in clinical trials: A systematic review in clinicaltrials.gov
by: Alaleh Sadraee, et al.
Published: (2021-05-01)

Clinical trials of stem cell-based therapies for pediatric diseases: a comprehensive analysis of trials registered on ClinicalTrials.gov and the ICTRP portal site
by: Yinwen Ji, et al.
Published: (2022-07-01)

Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications
by: Nick Boyne, et al.
Published: (2025-02-01)

Registered Clinical Trials for Artificial Intelligence in Lung Disease: A Scoping Review on ClinicalTrials.gov
by: Bingjie Li, et al.
Published: (2022-12-01)

Accelerating evidence synthesis for safety assessment through ClinicalTrials.gov platform: a feasibility study
by: Tianqi Yu, et al.
Published: (2024-07-01)

Systematic drug repositioning through mining adverse event data in ClinicalTrials.gov
by: Eric Wen Su, et al.
Published: (2017-03-01)

Characteristic of clinical trials related to traumatic brain injury registered on ClinicalTrials.gov over the past two decades (2004–2023)
by: Ruili Guo, et al.
Published: (2024-09-01)

Clinical trial reporting performance of thirty UK universities on ClinicalTrials.gov—evaluation of a new tracking tool for the US clinical trial registry
by: Sarai Mirjam Keestra, et al.
Published: (2021-06-01)

Worldwide Trends in Registering Real-World Studies at ClinicalTrials.gov: A Cross-Sectional Analysis
by: Li Y, et al.
Published: (2023-03-01)

Overcoming non-compliance with clinical trial registration and results reporting: One Institution's approach
by: Sarah H. Snider, et al.
Published: (2020-06-01)

Characteristics analysis of clinical trial registration for endodontic diseases based on the ClinicalTrials.gov and ChiCTR databases
by: LI Sha, GUO Jincai
Published: (2024-08-01)

Comprehensive overview of antibody drug-related clinical studies in gynecology: insights from ClinicalTrials.gov
by: Xiaoling Zhou, et al.
Published: (2025-05-01)

Evaluating the discoverability of supporting research materials in ClinicalTrials.gov for US federally funded COVID-19 clinical studies
by: Paije Wilson, et al.
Published: (2024-07-01)

Trends in Israeli clinical trials registration “MyTrial”
by: Anat Engel, et al.
Published: (2024-10-01)

CAR-T cell therapy clinical trials: global progress, challenges, and future directions from ClinicalTrials.gov insights
by: Li-Ya Cao, et al.
Published: (2025-05-01)

Impact of the COVID-19 Pandemic on Non-COVID-19 Clinical Trials
by: Katia Audisio, et al.
Published: (2022-01-01)

Effects of Peak Inspiratory Pressure-Guided Setting of Intracuff Pressure for Laryngeal Mask Airway Supreme™ Use during Laparoscopic Cholecystectomy: A Randomized Controlled Trial
by: Mao-Hua Wang, et al.
Published: (2021-09-01)

Improved clinical trial race/ethnicity reporting and updated inclusion profile, 2017–2022: A New Jersey snapshot
by: Elli Gourna Paleoudis, et al.
Published: (2024-06-01)

Characteristics of immunotherapy trials for nasopharyngeal carcinoma over a 15-year period
by: Huageng Huang, et al.
Published: (2023-08-01)

The Microbiome in Bronchial Biopsies from Smokers and Ex-Smokers with Stable COPD - A Metatranscriptomic Approach
by: B. Ditz, et al.
Published: (2022-12-01)

The landscape of investigator‐initiated oncology trials conducted in mainland China during the past decade (2010–2019)
by: Ye Cao, et al.
Published: (2023-02-01)

Distribution of trial registry numbers within full-text of PubMed Central articles: implications for linking trials to publications and indexing trial publication types
by: Arthur M. Holt, et al.
Published: (2025-01-01)

Insights into the adoption of innovative clinical trials across therapeutic areas using clinical trials registry data and large Language models
by: Danila Azzolina, et al.
Published: (2025-10-01)

Dissemination and outcome reporting bias in clinical malaria intervention trials: a cross-sectional analysis
by: Lydia Pool, et al.
Published: (2024-09-01)

Completeness and changes in data reporting pharmacological interventions to treat COVID-19
by: Mia Strikić, et al.
Published: (2025-07-01)

The Role and Challenges of Investigator‐Initiated Trials in the Cell and Gene Therapy Products Boom in Mainland China
by: Yifan Yang, et al.
Published: (2025-02-01)

Coronavirus Disease 2019 Related Clinical Studies: A Cross-Sectional Analysis
by: Lin-Lu Ma, et al.
Published: (2020-09-01)

Effects of human probiotics on memory and psychological and physical measures in community-dwelling older adults with normal and mildly impaired cognition: results of a bi-center, double-blind, randomized, and placebo-controlled clinical trial (CleverAge biota)
by: Ales Bartos, et al.
Published: (2023-07-01)

Comprehensive analysis of clinical research profiles and study characteristics of oral potentially malignant disorders: an observational study
by: Lijian Zhao, et al.
Published: (2024-10-01)

Characteristics of phase 4 clinical trials on Dental Caries registered at Clinicaltrials.gov
by: Kerim Safa Kul, et al.
Published: (2025-03-01)

Efficacy and safety of 308-nm Excimer lamp combined with Tacrolimus 0.1% ointment vs Tacrolimus 0.1% ointment as monotherapy in treating children with limited vitiligo: a randomized controlled trial
by: Diala Alshiyab, et al.
Published: (2024-12-01)

Characteristics of clinical trials of influenza and respiratory syncytial virus registered in ClinicalTrials.gov between 2014 and 2021
by: David Lora, et al.
Published: (2023-09-01)

Biomarkers for predicting atrial fibrillation: An explorative sub-analysis of the randomised SCREEN-AF trial
by: Katharina Schmalstieg-Bahr, et al.
Published: (2024-12-01)

A compound analysis of medical device clinical trials registered in Africa on clinicaltrials.gov
by: Brian Matovu, et al.
Published: (2024-10-01)

Reporting characteristics of nonsurgical periodontal therapy trials registered in ClinicalTrials.gov: an observational study
by: Petra Stazic, et al.
Published: (2023-07-01)